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CAS 37577-24-5

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(-)-Fenfluramine

Description:
(-)-Fenfluramine is a chemical compound primarily known for its use as an appetite suppressant in the treatment of obesity. It is a member of the phenethylamine class and is characterized by its chiral nature, with the (-) enantiomer being the active form. The compound has a molecular formula that includes carbon, hydrogen, nitrogen, and oxygen atoms, contributing to its structural complexity. (-)-Fenfluramine acts primarily as a serotonin releasing agent, influencing neurotransmitter levels in the brain, which can lead to reduced appetite. However, its use has been associated with serious cardiovascular side effects, leading to its withdrawal from the market in many countries. The compound is typically encountered as a white to off-white crystalline powder and is soluble in organic solvents. Its pharmacological profile has led to ongoing research into its potential therapeutic applications and safety concerns, particularly regarding long-term use. As with any pharmaceutical agent, understanding its chemical properties, mechanisms of action, and safety profile is crucial for its application in clinical settings.
Formula:C12H16F3N
InChI:InChI=1S/C12H16F3N/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15/h4-6,8-9,16H,3,7H2,1-2H3/t9-/m1/s1
InChI key:InChIKey=DBGIVFWFUFKIQN-SECBINFHSA-N
SMILES:C([C@H](NCC)C)C1=CC(C(F)(F)F)=CC=C1
Synonyms:
  • (-)-(R)-N-Ethyl-alpha-methyl-m-(trifluoromethyl)phenethylamine
  • (2R)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine
  • (R)-(-)-Fenfluramine
  • (αR)-N-Ethyl-α-methyl-3-(trifluoromethyl)benzeneethanamine
  • <span class="text-smallcaps">L</span>-Fenfluramine
  • Benzeneethanamine, N-ethyl-α-methyl-3-(trifluoromethyl)-, (R)-
  • Benzeneethanamine, N-ethyl-α-methyl-3-(trifluoromethyl)-, (αR)-
  • Fenfluramine
  • Fenfluramine l-form
  • Levofenfluramina
  • See more synonyms
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