CAS 375835-43-1

2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4,5,6-tetrahydropyridin-2-yl]sulfanyl}-N-(1,3-thiazol-2-yl)acetamide

Description:

The chemical substance known as 2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4,5,6-tetrahydropyridin-2-yl]sulfanyl}-N-(1,3-thiazol-2-yl)acetamide, with the CAS number 375835-43-1, is a complex organic compound characterized by its unique structural features. It contains a tetrahydropyridine ring, which contributes to its potential biological activity, and a thiazole moiety that may enhance its pharmacological properties. The presence of a cyano group and a sulfanyl linkage suggests potential reactivity and interaction with biological targets. This compound may exhibit various properties such as solubility in organic solvents, moderate stability under standard conditions, and potential for forming hydrogen bonds due to the presence of functional groups like amides and carbonyls. Its intricate structure indicates that it could be of interest in medicinal chemistry, particularly in the development of new therapeutic agents. However, specific physical and chemical properties such as melting point, boiling point, and solubility would require experimental determination or literature reference for precise values.

Formula: C₁₈H₁₆N₄O₂S₂

Synonyms:

• Necrostatin-34
• 2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4,5,6-tetrahydropyridin-2-yl]sulfanyl}-N-(1,3-thiazol-2-yl)acetamide
• nec-34
• 2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4
• 2-((3-Cyano-6-oxo-4-(p-tolyl)-1,4,5,6-tetrahydropyridin-2-yl)thio)-N-(thiazol-2-yl)acetamide

Necrostatin-34

CAS: 375835-43-1

Formula: C₁₈H₁₆N₄O₂S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 384.4752

Ref: IN-DA01X5OI

Necrostatin-34

CAS: 375835-43-1

Necrostatin-34

Purity: ≥95%

Molecular weight: 384.48g/mol

Ref: 54-BUP15186

Necrostatin-34

CAS: 375835-43-1

Necrostatin-34 (2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4) is a RIPK1 kinase inhibitor, stabilizing RIPK1 kinase in an inactive conformation by occupying a

Formula: C₁₈H₁₆N₄O₂S₂

Purity: 98.66% - 98.8%

Color and Shape: Solid

Molecular weight: 384.48

Ref: TM-T9095

Necrostatin-34

CAS: 375835-43-1

Necrostatin-34 is a medicinal compound that acts as an inhibitor of protein kinases. It is an analog of Necrostatin-1, which was originally discovered in Chinese hamster ovary cells. Necrostatin-34 has been found to have anticancer properties and can induce apoptosis in cancer cells. This compound blocks the activity of kinases involved in cell death pathways, preventing necrosis and promoting cell survival. Necrostatin-34 has shown promising results in tumor growth inhibition and may be a potential therapeutic agent for cancer treatment. The compound can be detected in urine samples and has been extensively studied as a potential anticancer drug.

Formula: C₁₈H₁₆N₄O₂S₂

Purity: Min. 95%

Molecular weight: 384.5 g/mol

Ref: 3D-AQA83543