CAS 3763-80-2

10H-Phenothiazine-10-propanamine, 2-chloro-, hydrochloride (1:1)

Description:

10H-Phenothiazine-10-propanamine, 2-chloro-, hydrochloride (1:1), commonly known by its CAS number 3763-80-2, is a chemical compound that belongs to the phenothiazine class, which is characterized by a tricyclic structure containing sulfur and nitrogen atoms. This compound typically exhibits properties associated with phenothiazines, including potential antipsychotic and antihistaminic activities. As a hydrochloride salt, it is usually more soluble in water, enhancing its bioavailability for pharmaceutical applications. The presence of the 2-chloro substituent may influence its pharmacological properties and reactivity. In terms of safety, like many phenothiazines, it may have side effects and requires careful handling due to its potential toxicity. Its applications may extend to medicinal chemistry, where it could be explored for therapeutic uses, particularly in the treatment of psychiatric disorders. Overall, this compound exemplifies the diverse functionalities and applications of phenothiazine derivatives in medicinal chemistry.

Formula: C₁₅H₁₅ClN₂S·ClH

InChI: InChI=1S/C15H15ClN2S.ClH/c16-11-6-7-15-13(10-11)18(9-3-8-17)12-4-1-2-5-14(12)19-15;/h1-2,4-7,10H,3,8-9,17H2;1H

InChI key: InChIKey=CLFAUWZDUIVBAN-UHFFFAOYSA-N

SMILES: C(CCN)N1C=2C(SC=3C1=CC=CC3)=CC=C(Cl)C2.Cl

Synonyms:

• 10H-Phenothiazine-10-propanamine, 2-chloro-, hydrochloride (1:1)
• 10H-Phenothiazine-10-propanamine, 2-chloro-, monohydrochloride
• 10H-phenothiazine-10-propanamine, 2-chloro-
• 2-Chloro-10-(3-aminopropyl)phenothiazine
• Didemethylchlorpromazine hydrochloride
• Didesmethylchlorpromazine hydrochloride
• Phenothiazine, 10-(3-aminopropyl)-2-chloro-, monohydrochloride
• Skf 4577A

Didesmethyl Chlorpromazine HCl

CAS: 3763-80-2

Formula: C₁₅H₁₅ClN₂S·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 290.82 36.46

Ref: 4Z-C-125007

Didesmethylchlorpromazine Hydrochloride

Controlled Product

CAS: 3763-80-2

Stability Hygroscopic
Applications Didesmethylchlorpromazine Hydrochloride is an impurity of Chlorpromazine (C424750) which has antiemetic; antipsychotic properties.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Anden, N.-E., et al.: Eur. J. Pharmacol., 11, 303 (1970), Curzon, G., et al.: Trends Pharmacol. Sci., 11, 61 (1990)

Formula: C₁₅H₁₆Cl₂N₂S

Color and Shape: Neat

Molecular weight: 327.27

Ref: TR-D440905

Didesmethylchlorpromazine hydrochloride

CAS: 3763-80-2

Didesmethylchlorpromazine hydrochloride is an antitumor agent that is resistant to multidrug resistance. It is a potent inhibitor of DNA synthesis and has been shown to sensitize resistant cells to other drugs. Didesmethylchlorpromazine hydrochloride was found to have cytotoxic activity against various human tumor cell lines, including multidrug-resistant cells. However, it did not show any significant activity against normal cells.

Formula: C₁₅H₁₆Cl₂N₂S

Purity: Min. 95%

Molecular weight: 327.3 g/mol

Ref: 3D-DAA76380

Didesmethyl Chlorpromazine

CAS: 3763-80-2

Formula: C₁₅H₁₅ClN₂SHCl

Molecular weight: 290.82 : 36.46

Ref: ST-EA-CP-C19028