CAS 376348-65-1: Maraviroc

Formula: C₂₉H₄₁F₂N₅O

InChI: InChI=1S/C29H41F2N5O/c1-19(2)27-34-33-20(3)36(27)25-17-23-9-10-24(18-25)35(23)16-13-26(21-7-5-4-6-8-21)32-28(37)22-11-14-29(30,31)15-12-22/h4-8,19,22-26H,9-18H2,1-3H3,(H,32,37)/t23-,24+,25-,26-/m0/s1

InChI key: InChIKey=GSNHKUDZZFZSJB-QYOOZWMWSA-N

SMILES: O=C(NC(C=1C=CC=CC1)CCN2C3CCC2CC(N4C(=NN=C4C(C)C)C)C3)C5CCC(F)(F)CC5

Synonyms:

• 4,4-Difluoro-N-[(1S)-3-[(3-exo)-3-[3-methyl-5-(1-methylethyl)-4H-1,2,4-triazol-4-yl]-8-azabicyclo[3.2.1]oct-8-yl]-1-phenylpropyl]cyclohexanecarboxamide
• 4,4-Difluoro-N-[(1S)-3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-phenylpropyl]cyclohexane-1-carboxamide
• UK 427857
• Maraviroc
• Celsentri
• Cyclohexanecarboxamide, 4,4-difluoro-N-[(1S)-3-[(3-exo)-3-[3-methyl-5-(1-methylethyl)-4H-1,2,4-triazol-4-yl]-8-azabicyclo[3.2.1]oct-8-yl]-1-phenylpropyl]-
• 4,4-difluoro-N-[(1S)-3-{(1R,5S)-3-[3-methyl-5-(1-methylethyl)-4H-1,2,4-triazol-4-yl]-8-azabicyclo[3.2.1]oct-8-yl}-1-phenylpropyl]cyclohexanecarboxamide
• 4,4-difluoro-N-[(1S)-3-{3-[3-methyl-5-(propan-2-yl)-4H-1,2,4-triazol-4-yl]-8-azabicyclo[3.2.1]oct-8-yl}-1-phenylpropyl]cyclohexanecarboxamide

Cyclohexanecarboxamide,4,4-difluoro-N-[(1S)-3-[(3-exo)-3-[3-methyl-5-(1-methylethyl)-4H-1,2,4-triazol-4-yl]-8-azabicyclo[3.2.1]oct-8-yl]-1-phenylpropyl]-

CAS: 376348-65-1

• Formula: C₂₉H₄₁F₂N₅O
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 513.6655

Maraviroc

CAS: 376348-65-1

• Formula: C₂₉H₄₁F₂N₅O
• Color and Shape: White To Off-White Solid
• Molecular weight: 513.68

Maraviroc

CAS: 376348-65-1

• Formula: C₂₉H₄₁F₂N₅O
• Purity: ≥ 97.0%
• Color and Shape: White to off-white crystalline powder
• Molecular weight: 513.67

Maraviroc

CAS: 376348-65-1

• Formula: C₂₉H₄₁F₂N₅O
• Color and Shape: Neat
• Molecular weight: 513.67

Maraviroc

CAS: 376348-65-1

• Formula: C₂₉H₄₁F₂N₅O
• Purity: >95.0%(HPLC)(qNMR)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 513.67

Maraviroc

CAS: 376348-65-1

Maraviroc: a CCR5 antagonist blocking HIV-1 entry; IC50s-MIP-1α: 3.3nM, MIP-1β: 7.2nM, RANTES: 5.2nM.

• Formula: C₂₉H₄₁F₂N₅O
• Purity: 100% - 99.55%
• Color and Shape: Brown Solid
• Molecular weight: 513.67

Maraviroc

CAS: 376348-65-1

• Formula: C₂₉H₄₁F₂N₅O
• Color and Shape: White To Off-White
• Molecular weight: 513.67

Maraviroc

CAS: 376348-65-1

CCR-5 chemokine receptor antagonist; inhibits HIV entry via gp120 protein

• Formula: C₂₉H₄₁F₂N₅O
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 513.67 g/mol