CAS 37654-41-4

6-ketoestriol 6-(O-carboxymethyl)oxime

Description:

6-Ketoestriol 6-(O-carboxymethyl)oxime, identified by its CAS number 37654-41-4, is a chemical compound that belongs to the class of steroid derivatives. It is characterized by the presence of a keto group at the 6-position of the estriol structure, along with an oxime functional group formed by the reaction of a carbonyl compound with hydroxylamine. The carboxymethyl group enhances its solubility and reactivity, making it suitable for various biochemical applications. This compound may exhibit biological activity, potentially influencing hormonal pathways due to its structural similarity to estrogen. Its properties, such as solubility, stability, and reactivity, can be influenced by the presence of functional groups, which may also affect its interaction with biological systems. As with many steroid derivatives, it is important to consider its potential pharmacological effects and applications in research, particularly in the fields of endocrinology and medicinal chemistry. Proper handling and safety measures should be observed when working with this compound in laboratory settings.

Formula: C₂₀H₂₅NO₆

InChI: InChI=1/C20H25NO6/c1-20-5-4-12-11-3-2-10(22)6-14(11)16(21-27-9-18(24)25)7-13(12)15(20)8-17(23)19(20)26/h2-3,6,12-13,15,17,19,22-23,26H,4-5,7-9H2,1H3,(H,24,25)/b21-16+/t12?,13?,15?,17-,19+,20+/m1/s1

Synonyms:

• Estriol-6-(O-carboxymethyl)oxime
• ({[(6E,8ξ,9ξ,14ξ,16α,17β)-3,16,17-trihydroxyestra-1,3,5(10)-trien-6-ylidene]amino}oxy)acetic acid
• Acetic acid, ((((16alpha,17beta)-3,16,17-trihydroxyestra-1,3,5(10)-trien-6-ylidene)amino)oxy)-

6-Oxoestriol (carboxymethyl)oxime

CAS: 37654-41-4

6-Oxoestriol (carboxymethyl)oxime is a synthetic estrogen. It is a water-soluble compound that can be stored at room temperature in the dark. This drug binds with high affinity to mammalian serum albumin, and has an elimination half-life of 2 hours. The binding constants for 6-oxoestriol (carboxymethyl)oxime and serum albumin are greater than 10,000 M-1. 6-Oxoestriol (carboxymethyl)oxime binds to the estrogen receptor, which mediates its effects on the uterus, mammary gland, and pituitary gland. 6-Oxoestriol (carboxymethyl)oxime is used therapeutically as a replacement for estrogen in cases of hypogonadism or menopause. This drug is also used experimentally to study the role of estrogen receptors in various tissues.

Formula: C₂₀H₂₅NO₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 375.4 g/mol

Ref: 3D-MBA65441