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CAS 376581-24-7

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QUINOLINE-6-BORONIC ACID

Description:
Quinoline-6-boronic acid is an organic compound characterized by the presence of a quinoline ring system substituted with a boronic acid functional group. This compound typically exhibits a pale yellow to off-white solid appearance and is soluble in polar solvents such as water and alcohols, owing to the boronic acid moiety. The boronic acid group is known for its ability to form reversible covalent bonds with diols, making quinoline-6-boronic acid useful in various applications, including medicinal chemistry and materials science. It can serve as a key intermediate in the synthesis of biologically active compounds and is often utilized in Suzuki-Miyaura cross-coupling reactions, which are pivotal in the formation of carbon-carbon bonds. Additionally, quinoline derivatives are recognized for their diverse biological activities, including antimicrobial and anticancer properties. The compound's reactivity and functional versatility make it a valuable tool in organic synthesis and drug development. Safety data should be consulted for handling and storage, as with any chemical substance.
Formula:C9H8BNO2
InChI:InChI=1/C9H8BNO2/c12-10(13)8-3-4-9-7(6-8)2-1-5-11-9/h1-6,12-13H
SMILES:c1cc2cc(ccc2nc1)B(O)O
Synonyms:
  • 6-Quinolineboronicaid
  • Quinolin-6-Yl-6-Boronic Acid
  • 6-Quinolylboronic Acid
  • Quinolin-6-ylboronic acid
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