CAS 376653-43-9

Ceftobiprole medocaril

Description:

Ceftobiprole medocaril is a broad-spectrum cephalosporin antibiotic, primarily used for the treatment of bacterial infections, particularly those caused by resistant strains. It is a prodrug, meaning it is converted into its active form, ceftobiprole, in the body. This compound exhibits a unique mechanism of action by binding to penicillin-binding proteins (PBPs), which inhibits bacterial cell wall synthesis, leading to cell lysis and death. Ceftobiprole is effective against a variety of Gram-positive and Gram-negative bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). Its pharmacokinetic profile allows for effective dosing regimens, and it is typically administered intravenously. The substance is characterized by its stability against certain beta-lactamases, which enhances its efficacy against resistant bacterial strains. Ceftobiprole medocaril has undergone clinical evaluations for conditions such as complicated skin and soft tissue infections and community-acquired pneumonia, demonstrating its potential in treating serious infections where traditional antibiotics may fail.

Formula: C₂₆H₂₆N₈O₁₁S₂

InChI: InChI=1S/C26H26N8O11S2/c1-10-14(45-26(41)44-10)8-43-25(40)32-4-3-13(7-32)33-5-2-11(20(33)36)6-12-9-46-22-16(21(37)34(22)17(12)23(38)39)28-19(35)15(30-42)18-29-24(27)47-31-18/h6,13,16,22,42H,2-5,7-9H2,1H3,(H,28,35)(H,38,39)(H2,27,29,31)/b11-6+,30-15-/t13-,16-,22-/m1/s1

InChI key: InChIKey=HFTSMHTWUFCYMJ-YIOMYIDASA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@H](NC(/C(=N\O)/C=3N=C(N)SN3)=O)C2=O)(SCC1/C=C\4/C(=O)N(CC4)[C@H]5CN(C(OCC=6OC(=O)OC6C)=O)CC5)[H]

Synonyms:

• (6R,7R)-7-[[(2Z)-2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(hydroxyimino)acetyl]amino]-3-[(E)-[(3′R)-1′-[[(5-methyl-2-oxo-1,3-dioxol-4-yl)methoxy]carbonyl]-2-oxo[1,3′-bipyrrolidin]-3-ylidene]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(5-amino-1,2,4-thiadiazol-3-yl)(hydroxyimino)acetyl]amino]-3-[(E)-[(3′R)-1′-[[(5-methyl-2-oxo-1,3-dioxol-4-yl)methoxy]carbonyl]-2-oxo[1,3′-bipyrrolidin]-3-ylidene]methyl]-8-oxo-, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(hydroxyimino)acetyl]amino]-3-[(E)-[(3′R)-1′-[[(5-methyl-2-oxo-1,3-dioxol-4-yl)methoxy]carbonyl]-2-oxo[1,3′-bipyrrolidin]-3-ylidene]methyl]-8-oxo-, (6R,7R)-
• Bal-5788
• Ceftobiprole medocaril
• Ro-65-5788
• Ro-65-5788/001
• Zeftera

Ceftobiprole medocaril

CAS: 376653-43-9

Ceftobiprole medocaril

Purity: ≥95%

Molecular weight: 690.66g/mol

Ref: 54-BUP01714

Ceftobiprole medocaril

CAS: 376653-43-9

Formula: C₂₀H₂₂N₈O₆S₂

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 534.57

Ref: 7W-GP0868

Ceftobiprole Medocaril

CAS: 376653-43-9

Formula: C₂₆H₂₆N₈O₁₁S₂

Molecular weight: 690.66

Ref: 4Z-C-349003

Ceftobiprole medocaril

CAS: 376653-43-9

Ceftobiprole medocaril: injectable prodrug; its active form fights broad-range infections including MRSA.

Formula: C₂₆H₂₆N₈O₁₁S₂

Purity: 98.15%

Color and Shape: Solid

Molecular weight: 690.66

Ref: TM-T40475

Ceftobiprole Medocaril

Controlled Product

CAS: 376653-43-9

Formula: C₂₆H₂₆N₈O₁₁S₂

Color and Shape: Neat

Molecular weight: 690.662

Ref: TR-C359450

Ceftobiprole medocaril

CAS: 376653-43-9

Ceftobiprole medocaril is a prodrug of the cephalosporin class, which is a beta-lactam antibiotic. It is synthetically derived, designed to combat Gram-positive and Gram-negative bacteria. The mode of action involves binding to penicillin-binding proteins (PBPs), crucial for bacterial cell wall synthesis, ultimately leading to bacterial cell lysis and death.

Formula: C₂₆H₂₆N₈O₁₁S₂

Purity: Min. 95%

Molecular weight: 690.66 g/mol

Ref: 3D-FC168067