CAS 37680-65-2

2,2′,5′-Trichlorobiphenyl

Description:

2,2′,5′-Trichlorobiphenyl, with the CAS number 37680-65-2, is a chlorinated biphenyl compound that belongs to the class of polychlorinated biphenyls (PCBs). It is characterized by the presence of three chlorine atoms attached to a biphenyl structure, specifically at the 2, 2', and 5' positions. This compound is typically a colorless to pale yellow solid at room temperature and is insoluble in water but soluble in organic solvents. 2,2′,5′-Trichlorobiphenyl exhibits thermal stability and resistance to degradation, which contributes to its persistence in the environment. It has been used in various industrial applications, including as a dielectric fluid in electrical equipment and as a heat transfer medium. However, due to its toxicological profile and potential environmental impact, including bioaccumulation and endocrine disruption, its production and use have been heavily regulated or banned in many countries. Safety measures are essential when handling this compound to mitigate exposure risks.

Formula: C₁₂H₇Cl₃

InChI: InChI=1/C12H7Cl3/c13-8-5-6-12(15)10(7-8)9-3-1-2-4-11(9)14/h1-7H

InChI key: InChIKey=DCMURXAZTZQAFB-UHFFFAOYSA-N

SMILES: ClC1=C(C=C(Cl)C=C1)C2=C(Cl)C=CC=C2

Synonyms:

• 1,1'-Biphenyl, 2,2',5-Trichloro-
• 1,1′-Biphenyl, 2,2′,5-trichloro-
• 2,2',5-Pcb
• 2,2',5-Trichloro-1,1'-biphenyl
• 2,2′,5-Trichloro-1,1′-biphenyl
• 2,2′,5-Trichlorobiphenyl
• 2,5,2'-Trichlorobiphenyl
• 37680-65-2
• CB 18 (chlorocarbon)
• Cb 18
• Pcb 18
• 2,2',5-Trichlorobiphenyl
• 2.2'.5-Trichlorobiphenyl 25mg [37680-65-2]
• 2,2',5-TRICB UNLABELED CERTIFIED STANDARD
• 2,5,2'-CB
• 2,2′,5-PCB
• 2,2',5-Trichlorobiphenyl-d5
• PCB NO 18
• BZ NO 18
• 2,2',5-Trichlorobiphenyl Solution in Toluene, 100μg/mL

PCB No 18

Controlled Product

CAS: 37680-65-2

PCB No. 18 is a polychlorinated biphenyl (PCB) that has been shown to be an endocrine disrupting chemical. PCB No. 18 is activated by diode or cavity and is used in human serum sample preparation for chromatographic science. This chemical has been found to have genotoxic potential, which may be due to its ability to bind covalently with DNA, RNA, and proteins. Sprague-Dawley rats were exposed to PCB No. 18 in their food at concentrations of 0, 200, 400, 1000 mg/kg/day for 13 weeks and the dry weight of the liver was measured at the end of the experiment. PCB No. 18 also showed dose-dependent uptake into rat tissues (liver, fat tissue) and caused some degree of hepatic injury as evidenced by increased levels of cytochrome P450 enzymes in the liver

Formula: C₁₂H₇Cl₃

Purity: Min. 95%

Molecular weight: 257.54 g/mol

Ref: 3D-MBA68065