CAS 37682-72-7

L-Valinamide, N2-[[[(1S)-1-carboxy-2-phenylethyl]amino]carbonyl]-L-arginyl-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-, hydrochloride (1:2)

Description:

L-Valinamide, N2-[[[(1S)-1-carboxy-2-phenylethyl]amino]carbonyl]-L-arginyl-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-, hydrochloride (1:2) is a complex organic compound characterized by its multi-functional structure, which includes amino acid derivatives and a hydrochloride salt form. This substance features a combination of an L-valinamide backbone and an L-arginine moiety, indicating its potential role in biological systems, particularly in peptide synthesis or as a pharmaceutical intermediate. The presence of multiple functional groups, such as carboxylic acids, amines, and imines, suggests that it may exhibit diverse reactivity and solubility properties. The hydrochloride form enhances its stability and solubility in aqueous environments, making it suitable for various applications in medicinal chemistry. Additionally, the compound's stereochemistry, particularly the (1S) configuration, is crucial for its biological activity, influencing interactions with biological targets. Overall, this compound's intricate structure and functional diversity position it as a significant entity in the study of bioactive molecules and therapeutic agents.

Formula: C₂₇H₄₄N₁₀O₆·2ClH

InChI: InChI=1S/C27H44N10O6.2ClH/c1-16(2)21(23(40)34-18(15-38)10-6-12-32-25(28)29)37-22(39)19(11-7-13-33-26(30)31)35-27(43)36-20(24(41)42)14-17-8-4-3-5-9-17;;/h3-5,8-9,15-16,18-21H,6-7,10-14H2,1-2H3,(H,34,40)(H,37,39)(H,41,42)(H4,28,29,32)(H4,30,31,33)(H2,35,36,43);2*1H

InChI key: InChIKey=YAHXZYICKJUJEO-UHFFFAOYSA-N

SMILES: C(C(NC(C(NC(CCCNC(=N)N)C=O)=O)C(C)C)=O)(NC(NC(CC1=CC=CC=C1)C(O)=O)=O)CCCNC(=N)N.Cl

Synonyms:

• <span class="text-smallcaps">L</smallcap>-Valinamide, N²-[[[(1S)-1-carboxy-2-phenylethyl]amino]carbonyl]-<smallcap>L</span>-arginyl-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-, dihydrochloride
• <span class="text-smallcaps">L</smallcap>-Valinamide, N²-[[[(1S)-1-carboxy-2-phenylethyl]amino]carbonyl]-<smallcap>L</span>-arginyl-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-, hydrochloride (1:2)
• Antipain dihydrochloride
• L-Valinamide, N(sup 2)-(((1-carboxy-2-phenylethyl)amino)carbonyl)-L-arginyl-N-(4-((aminoiminomethyl)amino)-1-formylbutyl)-, dihydrochloride
• N-({(1S)-4-[(diaminomethylidene)amino]-1-[(N-{4-[(diaminomethylidene)amino]-1-formylbutyl}-L-valyl)carbamoyl]butyl}carbamoyl)phenylalanine dihydrochloride
• L-Valinamide, N2-[[[(1S)-1-carboxy-2-phenylethyl]amino]carbonyl]-L-arginyl-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-, dihydrochloride
• L-Valinamide, N2-[[[(1S)-1-carboxy-2-phenylethyl]amino]carbonyl]-L-arginyl-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-, hydrochloride (1:2)

Antipain dihydrochloride

CAS: 37682-72-7

Antipain inhibits trypsin, papain, and catherpsins A and B (a reversible inhibitor of cysteine and serine proteases). It is used to evaluate the role of proteases in cell transformations. It is used to help identify new proteases. This Thermo Scientific brand product was originally part of the Alfa

Formula: C₂₇H₄₄N₁₀O₆•2HCl

Color and Shape: White, Powder

Molecular weight: 677.6

Ref: 02-J63680

Antipain dihydrochloride

CAS: 37682-72-7

Antipain dihydrochloride

Color and Shape: White To Pale Yellow Powder

Molecular weight: 677.62g/mol

Ref: 54-BIA0201

Antipain dihydrochloride

CAS: 37682-72-7

Antipain dihydrochloride (Antipain 2HCl) is a protease inhibitor derived from Actinomycetes with analgesic activity.

Formula: C₂₇H₄₆Cl₂N₁₀O₆

Purity: 95%

Color and Shape: White To Off-White Powder

Molecular weight: 677.62

Ref: TM-T26637

Antipain dihydrochloride

CAS: 37682-72-7

Formula: C₂₇H₄₄N₁₀O₆₂HCl

Molecular weight: 677.60

Ref: 7W-GL6582

Antipain (Synthetic)

CAS: 37682-72-7

Antipain (supplied as the HCl salt) is a cytosolic and bound form of antipain. It binds to ATP-binding cassette transporter proteins, which are involved in the transport of substances across cell membranes, and inhibits their enzymatic activity. Antipain 2HCI also has inhibitory properties on enzymes such as DNA polymerase II and pyruvate kinase. It has been shown to have an effect on biochemical properties such as protein synthesis, enzyme activities, and polymerase chain reactions. This drug has been shown to be effective in preventing myocardial infarcts and cellular apoptosis by inhibiting the release of cytochrome c from mitochondria. Antipain 2HCI may also have some anti-inflammatory effects due to its inhibition of prostaglandin synthesis.

Formula: C₂₇H₄₄N₁₀O₆·2HCl

Purity: Min. 95%

Molecular weight: 604.7 g/mol

Ref: 3D-IAP-3996-PI

Antipain dihydrochloride

CAS: 37682-72-7

Antipain 2HCI is a cytosolic and bound form of antipain. It binds to ATP-binding cassette transporter proteins, which are involved in the transport of substances across cell membranes, and inhibits their enzymatic activity. Antipain 2HCI also has inhibitory properties on enzymes such as DNA polymerase II and pyruvate kinase. It has been shown to have an effect on biochemical properties such as protein synthesis, enzyme activities, and polymerase chain reactions. This drug has been shown to be effective in preventing myocardial infarcts and cellular apoptosis by inhibiting the release of cytochrome c from mitochondria. Antipain 2HCI may also have some anti-inflammatory effects due to its inhibition of prostaglandin synthesis.

Formula: C₂₇H₄₄N₁₀O₆•(HCl)₂

Purity: Min. 95%

Molecular weight: 677.62 g/mol

Ref: 3D-FA29612