CAS 3770-63-6

(-)-Phenprocoumon

Description:

(-)-Phenprocoumon, with the CAS number 3770-63-6, is an anticoagulant medication primarily used in the prevention and treatment of thromboembolic disorders. It belongs to the class of coumarin derivatives and functions by inhibiting vitamin K epoxide reductase, which is essential for the synthesis of vitamin K-dependent clotting factors. This inhibition leads to a decrease in the production of these factors, thereby reducing blood coagulation. The substance is characterized by its chiral nature, existing as a single enantiomer, which contributes to its pharmacological activity. (-)-Phenprocoumon is typically administered orally and has a relatively long half-life, allowing for once-daily dosing in clinical settings. Its therapeutic effects are monitored through prothrombin time or INR (International Normalized Ratio) to ensure effective anticoagulation while minimizing the risk of bleeding. Additionally, it is important to consider potential interactions with other medications and dietary vitamin K, as these can significantly influence its efficacy and safety profile.

Formula: C₁₈H₁₆O₃

InChI: InChI=1S/C18H16O3/c1-2-13(12-8-4-3-5-9-12)16-17(19)14-10-6-7-11-15(14)21-18(16)20/h3-11,13,19H,2H2,1H3/t13-/m0/s1

InChI key: InChIKey=DQDAYGNAKTZFIW-ZDUSSCGKSA-N

SMILES: [C@@H](CC)(C1=C(O)C=2C(OC1=O)=CC=CC2)C3=CC=CC=C3

Synonyms:

• 4-Hydroxy-3-[(1S)-1-phenylpropyl]-2H-1-benzopyran-2-one
• Coumarin, 3-(α-ethylbenzyl)-4-hydroxy-, S-(-)-
• 2H-1-Benzopyran-2-one, 4-hydroxy-3-[(1S)-1-phenylpropyl]-
• (-)-Phenprocoumon
• 2H-1-Benzopyran-2-one, 4-hydroxy-3-(1-phenylpropyl)-, (S)-

(S)-Phenprocoumon

CAS: 3770-63-6

Formula: C₁₈H₁₆O₃

Molecular weight: 280.33

Ref: 4Z-P-114004

(S)-Phenprocoumon

Controlled Product

CAS: 3770-63-6

Applications (S)-Phenprocoumon acts primarily as an oral anti-coagulant.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kohl, C. et al.: Drug. Metab. Disp., 28, 161 (2000);

Formula: C₁₈H₁₆O₃

Color and Shape: Neat

Molecular weight: 280.318

Ref: TR-P318840