CAS 377090-84-1

(3Z)-3-(1H-imidazol-5-ylmethylidene)-5-methoxy-1,3-dihydro-2H-indol-2-one

Description:

The chemical substance known as (3Z)-3-(1H-imidazol-5-ylmethylidene)-5-methoxy-1,3-dihydro-2H-indol-2-one, with the CAS number 377090-84-1, is a complex organic compound characterized by its unique structural features. It contains an indole core, which is a bicyclic structure composed of a benzene ring fused to a pyrrole ring, contributing to its potential biological activity. The presence of the imidazole moiety suggests possible interactions with biological targets, particularly in medicinal chemistry. The methoxy group enhances its solubility and may influence its pharmacokinetic properties. This compound may exhibit various properties such as fluorescence, and its reactivity can be influenced by the functional groups present. Additionally, it may possess potential applications in drug development, particularly in the fields of oncology or infectious diseases, due to the biological significance of indole derivatives. However, detailed studies on its specific biological activity, toxicity, and pharmacological profile would be necessary to fully understand its potential uses.

Formula: C₁₃H₁₁N₃O₂

InChI: InChI=1/C13H11N3O2/c1-18-9-2-3-12-10(5-9)11(13(17)16-12)4-8-6-14-7-15-8/h2-7H,1H3,(H,14,15)(H,16,17)/b11-4-

SMILES: COc1ccc2c(c1)/C(=C/c1cnc[nH]1)/C(=N2)O

Synonyms:

• (3Z)-3-(1H-Imidazol-4-ylmethylene)-5-methoxy-1,3-dihydro-2H-indol-2-one
• 2H-Indol-2-one, 1,3-dihydro-3-(1H-imidazol-4-ylmethylene)-5-methoxy-, (3Z)-

SU 9516

CAS: 377090-84-1

Formula: C₁₃H₁₁N₃O₂

Molecular weight: 241.25

Ref: 7W-GL7837

SU9516

CAS: 377090-84-1

SU9516

Purity: ≥90%

Molecular weight: 241.25g/mol

Ref: 54-BUP08721

SU9516

CAS: 377090-84-1

SU9516 is a potent CDK2 inhibitor, with an IC50 of 22 nM, and also has inhibitory effects on CDK1 and CDK4, with IC50s of 40 nM and 200 nM, respectively.

Formula: C₁₃H₁₁N₃O₂

Purity: 99.34% - 99.87%

Color and Shape: Solid

Molecular weight: 241.25

Ref: TM-T6167

SU 9516

Controlled Product

CAS: 377090-84-1

Applications SU 9516 is a 3-substituted indolinone CDK inhibitor with potent and selective inhibition towards cyclin-dependant kinases.
References Moshinsky, D. et al.: Biochem. Biophys. Res. Comm., 310, 1026 (2003);

Formula: C₁₃H₁₁N₃O₂

Color and Shape: Neat

Molecular weight: 241.245

Ref: TR-S688045