3'-Deoxy-3'-C-methyl-5-fluorouridine, with the CAS number 37731-67-2, is a modified nucleoside analog of uridine. This compound features a fluorine atom at the 5-position of the uracil base, which enhances its antiviral properties, particularly against RNA viruses. The 3'-deoxy modification indicates the absence of a hydroxyl group at the 3' position of the ribose sugar, which is crucial for its incorporation into RNA and affects its ability to act as a substrate for RNA polymerases. The addition of a methyl group at the 3' position further alters its biochemical behavior, potentially influencing its stability and interaction with nucleic acid targets. This compound is of interest in medicinal chemistry and virology, as it may exhibit antiviral activity by interfering with viral replication processes. Its structural modifications contribute to its pharmacological profile, making it a candidate for further research in therapeutic applications.

3'-Deoxy-3'--C-methyl-5-fluorouridine

37731-67-2: 3'-Deoxy-3'-C-methyl-5-fluorouridine, with the CAS number 37731-67-2, is a modified nucleoside analog of uridine. This compound features a fluorine atom at the 5-position of the uracil base, which enhances its antiviral properties, particularly against RNA viruses. The 3'-deoxy modification indicates the absence of a hydroxyl group at the 3' position of the ribose sugar, which is crucial for its incorporation into RNA and affects its ability to act as a substrate for RNA polymerases. The addition of a methyl group at the 3' position further alters its biochemical behavior, potentially influencing its stability and interaction with nucleic acid targets. This compound is of interest in medicinal chemistry and virology, as it may exhibit antiviral activity by interfering with viral replication processes. Its structural modifications contribute to its pharmacological profile, making it a candidate for further research in therapeutic applications.

<p>3'-Deoxy-3'-a-C-methyl-5-fluorouridine is a Nucleoside Derivative - 3'-Modified nucleoside, 5-Modified pyrimidine nucleoside, Fluoro-modified nucleoside.</p>

3'-Deoxy-3'-a-C-methyl-5-fluorouridine

<p>3’-Deoxy-5-fluoro-3’-methyluridine is a nucleoside that has antiviral and anticancer properties. It is synthesized from 5-fluorouracil, which is a prodrug that is activated by 3’-deoxy-5-fluoro-3’-methyl uridine to produce 5′,6′ difluorodeoxyadenosine. This compound can be used in the treatment of hepatitis B virus and hepatitis C virus infections. 3’-Deoxy-5-fluoro-3’ methyluridine has also been shown to inhibit the growth of cancer cells in vitro.</p>

CAS 37731-67-2

3'-Deoxy-3'--C-methyl-5-fluorouridine

3'-Deoxy-3'-a-C-methyl-5-fluorouridine

Ref: TM-TNU0221

3’-Deoxy-5-fluoro-3’-methyluridine

Ref: 3D-ND144802