CAS 37759-72-1

2-Butenoic acid, 4-fluoro-, (2E)-

Description:

2-Butenoic acid, 4-fluoro-, (2E)-, also known by its CAS number 37759-72-1, is an unsaturated carboxylic acid characterized by the presence of a double bond between the second and third carbon atoms in its chain, along with a fluoro substituent at the fourth carbon. This compound typically exhibits a polar nature due to the carboxylic acid functional group, which can participate in hydrogen bonding, influencing its solubility in polar solvents like water. The (2E) designation indicates the specific geometric configuration of the double bond, which is in the trans configuration, affecting its reactivity and physical properties. The presence of the fluorine atom can enhance the acidity of the carboxylic group and may also influence the compound's reactivity in various chemical reactions, such as nucleophilic substitutions or additions. Overall, 2-butenoic acid, 4-fluoro-, (2E)- is of interest in organic synthesis and may have applications in pharmaceuticals or agrochemicals due to its unique structural features.

Formula: C₄H₅FO₂

5-(Chloromethyl)-2-ethoxypyridine

CAS: 37759-72-1

FK506 is a potent immunosuppressant that is structurally related to cyclosporin A. It binds to the cytosolic protein FKBP-12 and inhibits calcineurin, an enzyme that dephosphorylates the transcription factor NFAT. FK506 has been shown to be effective against depression and potent anticancer agents. FK506 also has anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. The compound is biosynthesized by the bacterium Streptomyces tsukubaensis, which produces a number of functional groups including fluorine and hexanoic acid.

Formula: C₈H₁₀ClNO

Purity: Min. 95%

Molecular weight: 171.62 g/mol

Ref: 3D-FC178920