CAS 37786-00-8

11-Deoxy-PGE1

Description:

11-Deoxy-PGE1, also known as 11-deoxy-prostaglandin E1, is a synthetic analog of prostaglandin E1 (PGE1) that exhibits various biological activities. It is characterized by its role as a vasodilator, which can help improve blood flow and reduce vascular resistance. This compound is often studied for its potential therapeutic applications, particularly in conditions related to cardiovascular health and pulmonary hypertension. Structurally, 11-Deoxy-PGE1 lacks a hydroxyl group at the 11th carbon position compared to its parent compound, which influences its biological activity and pharmacokinetics. It is typically administered in a clinical setting to manage specific medical conditions, and its effects are mediated through interactions with prostaglandin receptors. Additionally, 11-Deoxy-PGE1 is known for its ability to inhibit platelet aggregation, making it of interest in research related to thrombotic disorders. As with many prostaglandin derivatives, its stability and solubility in biological systems are important factors that influence its efficacy and safety profile in therapeutic applications.

Formula: C₂₀H₃₄O₄

InChI: InChI=1S/C20H34O4/c1-2-3-6-9-17(21)14-12-16-13-15-19(22)18(16)10-7-4-5-8-11-20(23)24/h12,14,16-18,21H,2-11,13,15H2,1H3,(H,23,24)/b14-12+/t16-,17-,18+/m0/s1

InChI key: InChIKey=DPNOTBLPQOITGU-LDDQNKHRSA-N

SMILES: C(CCCCCC(O)=O)[C@@H]1[C@@H](/C=C/[C@H](CCCCC)O)CCC1=O

Synonyms:

• 11-Deoxyprostaglandin E1
• (13E,15S)-15-Hydroxy-9-oxoprost-13-en-1-oic acid
• 15(S)-Hydroxy-9-oxo-13-trans-prostenoic acid
• (13E)-15-Hydroxy-9-oxoprost-13-enoic acid
• Prost-13-en-1-oic acid, 15-hydroxy-9-oxo-, (13E,15S)-

11-deoxy Prostaglandin E1

CAS: 37786-00-8

11-deoxy Prostaglandin E1 is a prostaglandin E1 analogue that has bronchodilator activity and can inhibit histamine-induced bronchoconstriction and cause

Formula: C₂₀H₃₄O₄

Color and Shape: Solid

Molecular weight: 338.48

Ref: TM-T36770