CAS 3779-59-7

(2S,4aR,5aS,7aR,7bR,8R,11S,12aS,13R,13aS,13bR,15aR)-11-(1-hydroxy-1-methylethyl)-1,1,7a,8,13a-pentamethyloctadecahydro-10,12a-epoxycyclopropa[1',8a']naphtho[2',1':4,5]indeno[2,1-b]oxepine-2,13-diol

Description:

The chemical substance with the name "(2S,4aR,5aS,7aR,7bR,8R,11S,12aS,13R,13aS,13bR,15aR)-11-(1-hydroxy-1-methylethyl)-1,1,7a,8,13a-pentamethyloctadecahydro-10,12a-epoxycyclopropa[1',8a']naphtho[2',1':4,5]indeno[2,1-b]oxepine-2,13-diol" and CAS number "3779-59-7" is a complex organic compound characterized by its intricate stereochemistry and multiple functional groups. This substance features a polycyclic structure, which includes a cyclopropane moiety and an epoxy group, contributing to its potential reactivity and biological activity. The presence of multiple methyl groups indicates a high degree of branching, which can influence its physical properties such as solubility and melting point. Additionally, the hydroxyl groups suggest that the compound may exhibit hydrogen bonding capabilities, affecting its interactions with other molecules. Such structural complexity often correlates with specific biological functions, making it of interest in fields such as medicinal chemistry and pharmacology. Overall, this compound exemplifies the diversity and intricacy found in organic chemistry, particularly in the context of natural product synthesis and modification.

Formula: C₃₀H₄₈O₅

InChI: InChI=1/C30H48O5/c1-16-14-17-22(25(4,5)33)35-30(34-17)21(16)26(6)12-13-29-15-28(29)11-10-20(31)24(2,3)18(28)8-9-19(29)27(26,7)23(30)32/h16-23,31-33H,8-15H2,1-7H3/t16-,17?,18+,19+,20+,21-,22+,23-,26-,27-,28-,29+,30+/m1/s1

Synonyms:

• 3779-59-7
• Cimicifugol
• Cimigenol

Cimigenol

CAS: 3779-59-7

Formula: C₃₀H₄₈O₅

Molecular weight: 488.70

Ref: 7W-GP2012

Cimigenol

CAS: 3779-59-7

Cimigenol is a potential antitumor compound, combination of it with an autophagy inhibitor may be a valuable strategy for the chemoprevention or treatment of colon cancer. It exerted potent cytotoxic activity against SMMC-7721 (7.87 µM) and A-549 (12.16 µM).

Formula: C₃₀H₄₈O₅

Purity: 95%~99%

Molecular weight: 488.709

Ref: BP-BP0357

Cimigenol

CAS: 3779-59-7

Cimigenol is an acetate extract from the plant Cimicifuga foetida. This extract has been shown to have antiproliferative and anticomplement activities, as well as a pharmacokinetic profile that is similar to epinephrine. It has been shown to induce autophagy in prostate cancer cells and inhibit the growth of fetal bovine retinal pigment epithelium cells. The mechanism of action of cimigenol is not yet known, but it may involve hydroxyl group reactions with proteins or epidermal growth factor (EGF) receptors on cell surfaces. Cimigenol also has anticancer properties that are mediated by its ability to reduce mitochondrial membrane potential (MMP).
CIMIGENOL- A potent acetate extract from the plant Cimicifuga foetida, which has been shown to have antiproliferative and anticomplement activities, as well as a pharmacokinetic profile that is similar to

Formula: C₃₀H₄₈O₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 488.7 g/mol

Ref: 3D-FC65351

Cimigenol

CAS: 3779-59-7

Cimigenol is a potential antitumor compound, combination of it with an autophagy inhibitor may be a valuable strategy for the chemoprevention or treatment of colon cancer. It exerted potent cytotoxic activity against SMMC-7721 (7.87μM) and A-549 (12.16 μM

Formula: C₃₀H₄₈O₅

Color and Shape: Solid

Molecular weight: 488.709

Ref: TM-TN1498