CAS 37793-53-6

N-10-(trifluoroacetyl)pteroic acid

Description:

N-10-(trifluoroacetyl)pteroic acid is a chemical compound that belongs to the class of pteroic acids, which are derivatives of folic acid. This substance features a trifluoroacetyl group attached to the nitrogen atom at the 10-position of the pteroic acid structure. The presence of the trifluoroacetyl group imparts unique properties, such as increased lipophilicity and potential biological activity. The compound is typically characterized by its molecular structure, which includes a bicyclic pteridine ring fused to a para-aminobenzoic acid moiety. It may exhibit solubility in organic solvents and limited solubility in water, depending on the specific conditions. N-10-(trifluoroacetyl)pteroic acid is of interest in biochemical research, particularly in studies related to folate metabolism and its derivatives. Its CAS number, 37793-53-6, is a unique identifier that facilitates the tracking and referencing of this compound in scientific literature and databases. As with many chemical substances, safety data sheets should be consulted for handling and toxicity information.

Formula: C₁₆H₁₁F₃N₆O₄

InChI: InChI=1/C16H11F3N6O4/c17-16(18,19)14(29)25(9-3-1-7(2-4-9)13(27)28)6-8-5-21-11-10(22-8)12(26)24-15(20)23-11/h1-5H,6H2,(H,27,28)(H3,20,21,23,24,26)

SMILES: c1cc(ccc1C(=O)O)N(Cc1cnc2c(c(nc(=N)[nH]2)O)n1)C(=O)C(F)(F)F

Synonyms:

• N10-(Trifluoroacetyl)pteroic acid
• 4-{[(2-Amino-4-Oxo-1,4-Dihydropteridin-6-Yl)Methyl](Trifluoroacetyl)Amino}Benzoic Acid
• Benzoic acid, 4-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl](2,2,2-trifluoroacetyl)amino]-

N10-Trifluoroacetylpteroic acid

CAS: 37793-53-6

Formula: C₁₆H₁₁F₃N₆O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 408.2915

Ref: IN-DA0033TW

4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl](2,2,2-trifluoroacetyl)amino]benzoic acid

CAS: 37793-53-6

4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl](2,2,2-trifluoroacetyl)amino]benzoic acid

Purity: 97%

Molecular weight: 408.29g/mol

Ref: 54-PC102296

4-{N-[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]-2,2,2-trifluoroacetamido}benzoic acid

CAS: 37793-53-6

Purity: 95%

Molecular weight: 408.2969970703125

Ref: 10-F600737

N10-(Trifluoroacetyl)pteroic acid

CAS: 37793-53-6

N10-(Trifluoroacetyl)pteroic acid

Purity: 97%

Molecular weight: 408.30g/mol

Ref: 54-PC99604

N10-(Trifluoroacetyl)pteroic acid

CAS: 37793-53-6

Pteroic acid is a ligand that binds to cholanic receptors in the cell membrane and induces the uptake of ethylene. This process is receptor-mediated and can be inhibited by folic and hydrophobic molecules, such as N10-(Trifluoroacetyl)pteroic acid. Pteroic acid is an important precursor of folic acid, which plays an important role in DNA synthesis and amino acid metabolism. Pteroic acid also has a hydrophobic nature that facilitates its binding to cells through hydrophobic interactions.

Formula: C₁₆H₁₁F₃N₆O₄

Purity: Min. 95 Area-%

Color and Shape: White Powder

Molecular weight: 408.29 g/mol

Ref: 3D-FT30146

N10-Trifluoroacetylpteroic Acid

Controlled Product

CAS: 37793-53-6

Stability Hygroscopic
Applications N10-Trifluoroacetylpteroic acid is a derivative of Pteroic acid (P840110), both of which are used as reagents to synthesize target ligands, like Folic acid (F680300), that have the ability to deliver chemotherapeutic agents specifically to cancer cells.
References Leamon, C., et al.: Bioconjugate Chem., 14, 738 (2003); Leamon, C., et al.: J. Drug Target., 7, 157 (1999); Yonghua, Z., et al.: Anal. Biochem., 332, 168 (2004)

Formula: C₁₆H₁₁F₃N₆O₄

Color and Shape: Neat

Molecular weight: 408.29

Ref: TR-T789700