CAS 378-44-9

Betamethasone

Description:

Betamethasone is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties, commonly used in the treatment of various conditions such as allergies, skin disorders, and autoimmune diseases. It is characterized by its potent glucocorticoid activity, which helps reduce inflammation and modulate the immune response. Betamethasone has a molecular formula that reflects its steroid structure, typically featuring a cyclopentanoperhydrophenanthrene core, with specific functional groups that enhance its biological activity. The substance is often administered in various forms, including topical creams, injections, and oral tablets, depending on the condition being treated. Its pharmacokinetics involve rapid absorption and metabolism, with a relatively long half-life compared to other corticosteroids, allowing for less frequent dosing. However, prolonged use can lead to side effects such as adrenal suppression, weight gain, and increased susceptibility to infections. As with any medication, it is essential to use betamethasone under medical supervision to manage potential risks and benefits effectively.

Formula: C₂₂H₂₉FO₅

InChI: InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1

InChI key: InChIKey=UREBDLICKHMUKA-DVTGEIKXSA-N

SMILES: F[C@@]12[C@]([C@]3([C@](C)(C[C@@H]1O)[C@](C(CO)=O)(O)[C@@H](C)C3)[H])(CCC=4[C@]2(C)C=CC(=O)C4)[H]

Synonyms:

• (11Beta,16Alpha)-9-Fluoro-11,17,21-Trihydroxy-16-Methylpregna-1,4-Diene-3,20-Dione
• (11β,16β)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
• 9-Fluoro-11,17,21-Trihydroxy-16-Methylpregna-1,4-Diene-3,20-Dione
• 9-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione
• 9-Fluoro-16β-methylprednisolone
• 9A-Fluoro-11B,17A,21-Trihydroxy-16B-Methylpregna-1,4-Diene-3,20-Dione
• 9Alpha-Fluoro-16Beta-Methylprednisolone
• 9α-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione
• 9α-Fluoro-16β-methyl-1,4-pregnadiene-11β,17α,21-triol-3,20-dione
• 9α-Fluoro-16β-methylprednisolone
• Becort
• Bedifos
• Betacorlan
• Betacortil
• Betacortril
• Betadexamethasone
• Betametasona
• Betametasone
• Betamethason
• Betamethasone base
• Betamethazone
• Betapredol
• Betasolon
• Bethamethasone
• Betnelan
• Betsolan
• Bifas
• Celestan
• Celestene
• Celeston
• Celestone
• Cidoten
• Colircusi betamida
• Dermabet
• Desacort-Beta
• Diprospan
• Ethamethasoneb
• Flosteron
• Flubenisolone
• Nsc 39470
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, (11β,16β)-
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16β-methyl-
• Rinderon
• Rinderon A
• Sch 4831
• Visubeta
• β-Methasone
• β-Methasone alcohol

Betamethasone - Bio-X ™

Controlled Product

CAS: 378-44-9

Betamethasone is a potent anti-inflammatory agent that belongs to the group of corticosteroids. It is used in the treatment of a number of inflammatory diseases, such as allergic states, dermatologic disorders and gastrointestinal disorders. This drug binds to glucocorticoid receptors inhibiting inflammatory signals whilst promoting anti-inflammatory signals.

Formula: C₂₂H₂₉FO₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 392.46 g/mol

Ref: 3D-BB300033

Betamethasone

Controlled Product

CAS: 378-44-9

Betamethasone is a synthetic corticosteroid, which is an analogue of a glucocorticoid sourced from adrenal cortex hormones. Its mode of action involves modulating the immune response by inhibiting the release of substances in the body that cause inflammation. This is achieved through its binding affinity to glucocorticoid receptors, leading to transcriptional changes that suppress pro-inflammatory cytokine production and other mediators of inflammation.

Formula: C₂₂H₂₉FO₅

Purity: Min. 97 Area-%

Color and Shape: White Powder

Molecular weight: 392.46 g/mol

Ref: 3D-FB18562

Betamethasone

CAS: 378-44-9

Purity: 95%

Molecular weight: 392.4670105

Ref: 10-F814067

9a-Fluoro-11b,17a,21-trihydroxy-16b-methylpregna-1,4-diene-3,20-dione

CAS: 378-44-9

Formula: C₂₂H₂₉FO₅

Purity: 99%

Color and Shape: Solid

Molecular weight: 392.4611

Ref: IN-DA0034IN