CAS 3788-44-1

H-Tyr-His-OH

Description:

H-Tyr-His-OH, also known as Tyr-His or Tyrosyl-Histidine, is a dipeptide composed of the amino acids tyrosine and histidine. It is characterized by the presence of a phenolic hydroxyl group from tyrosine, which contributes to its potential antioxidant properties. The histidine residue introduces an imidazole side chain, allowing for unique interactions in biological systems, such as metal ion coordination and proton transfer, which are crucial in enzymatic reactions. This dipeptide is soluble in water and exhibits a zwitterionic nature at physiological pH, making it relevant in various biochemical contexts, including peptide synthesis and drug development. H-Tyr-His-OH can also play a role in signaling pathways and may have implications in neurochemistry due to the involvement of its constituent amino acids in neurotransmitter systems. Its CAS number, 3788-44-1, allows for easy identification in chemical databases, facilitating research and application in fields such as biochemistry and pharmacology.

Formula: C₁₅H₁₈N₄O₄

Synonyms:

• Histidine,N-L-tyrosyl-, L-
• Histidine, N-tyrosyl-
• L-Histidine,N-L-tyrosyl-
• 21: PN: JP2006180840 SEQID: 19 unclaimed protein
• 21: PN:JP2006180841 SEQID: 19 unclaimed protein
• 44: PN: US20090104234 SEQID: 44unclaimed protein
• Tyrosylhistidine
• L-Histidine, L-tyrosyl-

H-Tyr-His-OH

CAS: 3788-44-1

Both single-dose administration and repetitive oral application of the dipeptide YH significantly decreased blood pressure in spontaneously hypertensive rats.

Formula: C₁₅H₁₈N₄O₄

Purity: ≥ 99%

Color and Shape: White

Molecular weight: 318.33

Ref: 01-4001846

H-Tyr-His-OH

CAS: 3788-44-1

Formula: C₁₅H₁₈N₄O₄

Molecular weight: 318.3278

Ref: IN-DA00C661

Tyrosylhistidine

CAS: 3788-44-1

Tyrosylhistidine (Tyr-His) is a dipeptide formed from tyrosine and histidine that exhibits orally active antihypertensive properties, demonstrated by its

Formula: C₁₅H₁₈N₄O₄

Color and Shape: Solid

Molecular weight: 318.33

Ref: TM-T80908

H-Tyr-His-OH

CAS: 3788-44-1

H-Tyr-His-OH is a trifluoroacetic acid derivative that is a histidine odorant. It can be used as a substitute for histidine in the detection of blood pressure, due to its ability to bind to nitric oxide and histidine receptors. H-Tyr-His-OH has been shown to have immunological properties, and it has been used as an immunogen in the production of monoclonal antibodies against human erythrocytes. H-Tyr-His-OH is also considered to be a potential biomarker because it can be detected by LC-MS/MS methods.

Formula: C₁₅H₁₈N₄O₄

Purity: Min. 95%

Molecular weight: 318.33 g/mol

Ref: 3D-FT108209