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CAS 379-34-0

:

Hydroxyphenobarbital

Description:
Hydroxyphenobarbital, with the CAS number 379-34-0, is a derivative of phenobarbital, a barbiturate that acts as a central nervous system depressant. This compound is characterized by the presence of a hydroxyl group (-OH) attached to the phenyl ring, which enhances its solubility and alters its pharmacological properties compared to its parent compound. Hydroxyphenobarbital exhibits anticonvulsant properties and is primarily used in the treatment of epilepsy and other seizure disorders. It is known for its sedative effects and can influence the metabolism of various drugs due to its interaction with liver enzymes. The substance is typically administered in a clinical setting, and its pharmacokinetics involve absorption, distribution, metabolism, and excretion that are influenced by factors such as dosage and individual patient characteristics. Safety and efficacy are paramount, and potential side effects may include drowsiness, dizziness, and dependence with prolonged use. As with all medications, it is essential to use hydroxyphenobarbital under medical supervision to mitigate risks and monitor therapeutic outcomes.
Formula:C12H12N2O4
InChI:InChI=1S/C12H12N2O4/c1-2-12(7-3-5-8(15)6-4-7)9(16)13-11(18)14-10(12)17/h3-6,15H,2H2,1H3,(H2,13,14,16,17,18)
InChI key:InChIKey=IEPXMKJNWPXDBP-UHFFFAOYSA-N
SMILES:C(C)C1(C(=O)NC(=O)NC1=O)C2=CC=C(O)C=C2
Synonyms:
  • 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-(4-hydroxyphenyl)-
  • 4-Hydroxyphenobarbital
  • 5-(p-Hydroxyphenyl)-5-ethylbarbituric acid
  • 5-Ethyl-5-(4-hydroxyphenyl)-2,4,6(1H,3H,5H)-pyrimidinetrione
  • 5-Ethyl-5-(4-hydroxyphenyl)barbituric acid
  • 5-Ethyl-5-(p-hydroxyphenyl)barbituric acid
  • 5-ethyl-5-(4-hydroxyphenyl)pyrimidine-2,4,6(1H,3H,5H)-trione
  • Barbituric acid, 5-ethyl-5-(p-hydroxyphenyl)-
  • Hydroxyphenobarbital
  • NSC 159266
  • See more synonyms
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Found 2 products.
  • 4-Hydroxy Phenobarbital
    TRC
    + Info

    4-Hydroxy Phenobarbital

    Controlled Product
    CAS:
    <p>Applications A metabolite of Phenobarbital.<br>References Philip,A. and Carroll, F.I.: Organic Prep. and Procedures Int., 7(3), 117 (1975),<br></p>
    Formula:C12H12N2O4
    Color and Shape:Neat
    Molecular weight:248.23

    Ref: TR-H948960

    5mg
    270.00€
    50mg
    1,734.00€
  • 4-Hydroxy Phenobarbital (1 mg/ml in Acetonitrile)
    TRC
    + Info

    4-Hydroxy Phenobarbital (1 mg/ml in Acetonitrile)

    Controlled Product
    CAS:
    Formula:C12H12N2O4
    Color and Shape:Single Solution
    Molecular weight:248.23

    Ref: TR-KIT5175

    5x1ml
    1,022.00€