CAS 379-79-3

Ergotamine tartrate

Description:

Ergotamine tartrate is a pharmaceutical compound derived from ergot alkaloids, primarily used in the treatment of migraine headaches. It is a semi-synthetic derivative of ergotamine, which is obtained from the fungus Claviceps purpurea. This compound is characterized by its ability to constrict blood vessels, thereby alleviating migraine symptoms. Ergotamine tartrate is typically administered in the form of tablets or sublingual formulations, allowing for rapid absorption and onset of action. The substance is known for its potential side effects, including nausea, vomiting, and cardiovascular complications, particularly when used inappropriately or in excessive doses. It acts primarily as a selective agonist for serotonin receptors, particularly the 5-HT1B and 5-HT1D subtypes, which play a crucial role in regulating vascular tone and neurotransmitter release. Due to its pharmacological properties, ergotamine tartrate is classified as a controlled substance in some jurisdictions, necessitating careful monitoring and prescription by healthcare professionals.

Formula:C₃₃H₃₅N₅O₅C₄H₆O₆

InChI:InChI=1S/C33H35N5O5.C4H6O6/c1-32(35-29(39)21-15-23-22-10-6-11-24-28(22)20(17-34-24)16-25(23)36(2)18-21)31(41)38-26(14-19-8-4-3-5-9-19)30(40)37-13-7-12-27(37)33(38,42)43-32;5-1(3(7)8)2(6)4(9)10/h3-6,8-11,15,17,21,25-27,34,42H,7,12-14,16,18H2,1-2H3,(H,35,39);1-2,5-6H,(H,7,8)(H,9,10)/t21-,25-,26+,27+,32-,33+;1-,2-/m11/s1

InChI key:InChIKey=NMTWKEWYQXZGCI-LYOWLMOVSA-N

SMILES:O[C@@]12N([C@@H](CC3=CC=CC=C3)C(=O)N4[C@]1(CCC4)[H])C(=O)[C@@](NC(=O)[C@@H]5C=C6C=7C=8C(C[C@]6(N(C)C5)[H])=CNC8C=CC7)(C)O2.[C@@H]([C@H](C(O)=O)O)(C(O)=O)O

Synonyms:

(5'Alpha)-5'-Benzyl-12'-Hydroxy-2'-Methyl-3',6',18-Trioxoergotaman 2,3-Dihydroxybutanedioate (1:1)
(5'alpha)-12'-hydroxy-2'-methyl-5'-(phenylmethyl)-Ergotaman-3',6',18-trione, [R-(R*,R*)]-2,3-dihydroxybutanediate (2:1) (salt)
Ergam
Ergate
Ergomar
Ergostat
Ergotaman-3',6',18-trione, 12'-hydroxy-2'-methyl-5'-(phenylmethyl)-, (5'alpha)-, [R-(R*,R*)]-2,3-dihydroxybutanedioate (2:1) (salt)
Ergotaman-3′,6′,18-trione, 12′-hydroxy-2′-methyl-5′-(phenylmethyl)-, (5α)-, (2R,3R)-2,3-dihydroxybutanedioate (2:1)
Ergotaman-3′,6′,18-trione, 12′-hydroxy-2′-methyl-5′-(phenylmethyl)-, (5′α)-, (2R,3R)-2,3-dihydroxybutanedioate (2:1) (salt)
Ergotaman-3′,6′,18-trione, 12′-hydroxy-2′-methyl-5′-(phenylmethyl)-, (5′α)-, [R-(R*,R*)]-2,3-dihydroxybutanedioate (2:1) (salt)
Ergotamine Bitartrate
Ergotamine, tartrate (2:1) (salt)
Ergotartrat
Etin
Exmigra
Femergin
Gotamine
Gotamine tartrate
Gynergen
Gynergin
Lingraine
Lingran
Medihaler-ergotamine
NSC 41869
Neo-Ergotin
Rigetamin
Secagyn
Secupan
Ergotamine tartrate
ergotaminebitartrate
ergotartrate
6’,18-trione,12’-hydroxy-2’-methyl-5’-(phenylmethyl)-ergotaman-3(5’alpha)
-,[theta-(theta,theta)]-2,3-dihydroxybutanedioate(2:1)(salt)
See more synonyms

Purity (%)

100

Found 9 products.

+ Info
Ergotamine Tartrate
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 379-79-3
Molecular weight:656.70
Ref: 3U-X8164
250mg
793.00€
VAT not included
Add to cart
+ Info
Ergotamine Tartrate
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 379-79-3
Color and Shape:Neat
Ref: 86-MM0097.00
250mg
270.00€
VAT not included
Add to cart
+ Info
Ergotamine D-Tartrate
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 379-79-3
Color and Shape:Neat
Ref: LP-ERG-803-TA-10
10mg
378.00€
VAT not included
Add to cart
50mg
1,631.00€
VAT not included
Add to cart
100mg
To inquire
Add to cart
+ Info
Ergotamine D-tartrate
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 379-79-3
<p>Ergotamine D-tartrate is a drug that belongs to the group of nonsteroidal anti-inflammatory drugs. It is used in the treatment of migraine and other headaches. Ergotamine D-tartrate inhibits the production of nitric oxide, which has been shown to be involved in the process of angiogenesis. This drug also has long-term efficacy for headaches and migraines, as well as an anti-migraine effect. Ergotamine D-tartrate binds to specific receptors on neurons called alpha2 adrenergic receptors, which are located on blood vessels in the brain and have been implicated in migraine pathophysiology. These receptors are not present on vessels elsewhere in the body, which makes ergotamine a more selective drug for migraine than other nonsteroidal anti-inflammatory drugs.</p>
Formula:(C₃₃H₃₅N₅O₅)₂•C₄H₆O₆
Purity:Min. 95%
Molecular weight:1,313.44 g/mol
Ref: 3D-FE30656
1g
940.00€
VAT not included
Add to cart
50mg
184.00€
VAT not included
Add to cart
100mg
240.00€
VAT not included
Add to cart
250mg
433.00€
VAT not included
Add to cart
500mg
657.00€
VAT not included
Add to cart
+ Info
ERGOTAMINE TARTRATE CRS - * DRUG PRECURSOR
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 379-79-3
ERGOTAMINE TARTRATE CRS - * DRUG PRECURSOR
Formula:C₇₀H₇₆N₁₀O₁₆
Color and Shape:Powder
Molecular weight:1313.41
Ref: 41-E1200000
100mg
115.00€
VAT not included
Add to cart
+ Info
ERGOTAMINE FOR SYSTEM SUITABILITY CRS - * DRUG PRECURSOR (ERGOTAMINE TARTRATE)
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 379-79-3
ERGOTAMINE FOR SYSTEM SUITABILITY CRS - * DRUG PRECURSOR (ERGOTAMINE TARTRATE)
Formula:C₇₀H₇₆N₁₀O₁₆
Color and Shape:Powder
Molecular weight:1313.41
Ref: 41-Y0001851
10mg
115.00€
VAT not included
Add to cart
+ Info
ERGOTAMINE TARTRATE RS - * DRUG PRECURSOR
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 379-79-3
ERGOTAMINE TARTRATE RS - * DRUG PRECURSOR
Formula:C₇₀H₇₆N₁₀O₁₆
Color and Shape:Powder
Molecular weight:1313.41
Ref: 41-ICRS0297
50mg
102.00€
VAT not included
Add to cart
+ Info
Ergotamine Tartrate
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 379-79-3
Ergotamine and its salts
Formula:(C₃₃H₃₅N₅O₅)₂·C₄H₆O₆
Color and Shape:White Yellow Powder
Molecular weight:1162.52764
Ref: 45-1241506
+ Info
Ergotamine tartrate
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 379-79-3
Ergotamine tartrate
Color and Shape:White
Ref: 47-141
200mg
Discontinued
Request information
Discontinued product

CAS 379-79-3

Ergotamine tartrate

Ergotamine Tartrate

Ref: 3U-X8164

Ergotamine Tartrate

Ref: 86-MM0097.00

Ergotamine D-Tartrate

Ref: LP-ERG-803-TA-10

Ergotamine D-tartrate

Ref: 3D-FE30656

ERGOTAMINE TARTRATE CRS - * DRUG PRECURSOR

Ref: 41-E1200000

ERGOTAMINE FOR SYSTEM SUITABILITY CRS - * DRUG PRECURSOR (ERGOTAMINE TARTRATE)

Ref: 41-Y0001851

ERGOTAMINE TARTRATE RS - * DRUG PRECURSOR

Ref: 41-ICRS0297

Ergotamine Tartrate

Ref: 45-1241506

Ergotamine tartrate

Ref: 47-141