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CAS 37927-01-8

:

(11β,16α,17α)-9-Fluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylic acid

Description:
The chemical substance known as (11β,16α,17α)-9-Fluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylic acid, with the CAS number 37927-01-8, is a synthetic corticosteroid. It is characterized by its fluorinated structure, which enhances its anti-inflammatory and immunosuppressive properties. The presence of hydroxyl groups at the 11 and 17 positions contributes to its biological activity, while the 16-methyl and 3-oxo groups are essential for its steroid framework. This compound is typically used in the treatment of various inflammatory conditions and may exhibit a range of pharmacological effects, including modulation of immune responses. Its unique structural features allow it to interact with glucocorticoid receptors, leading to the regulation of gene expression involved in inflammation and immune function. As with many corticosteroids, careful consideration of dosage and potential side effects is necessary when used therapeutically.
Formula:C21H27FO5
InChI:InChI=1S/C21H27FO5/c1-11-8-15-14-5-4-12-9-13(23)6-7-18(12,2)20(14,22)16(24)10-19(15,3)21(11,27)17(25)26/h6-7,9,11,14-16,24,27H,4-5,8,10H2,1-3H3,(H,25,26)/t11-,14+,15+,16+,18+,19+,20+,21+/m1/s1
InChI key:InChIKey=PFAGPIFFRLDBRN-AFKBWYBQSA-N
SMILES:F[C@@]12[C@]([C@]3([C@](C)(C[C@@H]1O)[C@](C(O)=O)(O)[C@H](C)C3)[H])(CCC=4[C@]2(C)C=CC(=O)C4)[H]
Synonyms:
  • Androsta-1,4-diene-17-carboxylic acid, 9-fluoro-11,17-dihydroxy-16-methyl-3-oxo-, (11β,16α,17α)-
  • (11β,16α,17α)-9-Fluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylic acid
  • 9-Fluoro-11β,17-dihydroxy-16α-methyl-3-oxoandrosta-1,4-diene-17β-carboxylic acid
  • (-)-Dexamethasone acid
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