CAS 379270-38-9

L-Alanine,N-[(S)-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]phenoxyphosphinyl]-, 1-methylethyl ester, (2E)-2-butenedioate (1:1)

Description:

L-Alanine, N-[(S)-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]phenoxyphosphinyl]-, 1-methylethyl ester, (2E)-2-butenedioate (1:1), with CAS number 379270-38-9, is a complex organic compound characterized by its unique structural features that include an amino acid backbone (L-Alanine), a purine derivative, and a phosphinyl group. This compound exhibits properties typical of both amino acids and phosphonates, making it potentially useful in biochemical applications, such as in drug design or as a biochemical probe. The presence of the purine moiety suggests possible interactions with nucleic acids or enzymes, while the phosphinyl group may confer stability and enhance biological activity. Additionally, the ester functionality indicates that it may undergo hydrolysis, which could be relevant in metabolic processes. Overall, this compound's intricate structure and functional groups suggest a multifaceted role in biological systems, warranting further investigation into its potential applications in medicinal chemistry and biochemistry.

Formula: C₂₁H₂₉N₆O₅P・C₄H₄O₄

Synonyms:

• Tenofovir Alafenamide Fumarate
• GS-7340 (fuMarate)

GS-7340 (fumarate)

CAS: 379270-38-9

Formula: C₂₅H₃₃N₆O₉P

Purity: 98%

Color and Shape: Solid

Molecular weight: 592.5381

Ref: IN-DA00C6J2

Tenofovir alafenamide fumarate

CAS: 379270-38-9

Tenofovir alafenamide fumarate

Purity: ≥98%

Molecular weight: 592.54g/mol

Ref: 54-BUP10199

(S)-Isopropyl 2-(((S)-((((R)-1-(6-Amino-9H-Purin-9-Yl)Propan-2-Yl)Oxy)Methyl)(Phenoxy)Phosphoryl)Amino)Propanoate Fumarate

CAS: 379270-38-9

(S)-Isopropyl 2-(((S)-((((R)-1-(6-Amino-9H-Purin-9-Yl)Propan-2-Yl)Oxy)Methyl)(Phenoxy)Phosphoryl)Amino)Propanoate Fumarate

Purity: 98%

Molecular weight: 592.54g/mol

Ref: 54-OR1027871

Tenofovir Alafenamide Fumarate

CAS: 379270-38-9

Formula: C₂₁H₂₉N₆O₅P·C₄H₄O₄

Color and Shape: White To Off-White Solid

Molecular weight: 476.48 116.07

Ref: 4Z-T-0260

Tenofovir Alafenamide Fumarate

Controlled Product

CAS: 379270-38-9

Applications Tenofovir Alafenamide Fumarate is a prodrug of Tenofovir (T018500), which is a reverse transcriptase inhibitor used to treat HIV and Hepatitis B. Antiviral.
References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007),

Formula: C₂₁H₂₉N₆O₅P·C₄H₄O₄

Color and Shape: Neat

Molecular weight: 592.5381

Ref: TR-T779380

Tenofovir Alafenamide Fumarate

CAS: 379270-38-9

Formula: C₂₁H₂₉N₆O₅PC₄H₄O₄

Molecular weight: 476.5 : 116.1

Ref: ST-EA-CP-T5023

Tenofovir alafenamide fumarate

CAS: 379270-38-9

Tenofovir alafenamide fumarate is a prodrug of tenofovir, an active antiretroviral agent. Tenofovir binds to the viral polymerase and blocks the synthesis of viral DNA. Tenofovir alafenamide fumarate is a prodrug that undergoes hydrolysis to form tenofovir. It has been shown to inhibit growth factor-β1, which may reduce the risk of opportunistic infections in people with HIV or AIDS. Tenofovir alafenamide fumarate has also been shown to be effective as an antiviral prophylaxis when used in combination with other drugs for active antiretroviral therapy.

Formula: C₂₁H₂₉N₆O₅P•C₄H₄O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 592.54 g/mol

Ref: 3D-FT76561

Tenofovir alafenamide fumarate

CAS: 379270-38-9

Tenofovir alafenamide fumarate (GS-7340) is an oral anti-HIV drug that prevents infection.

Formula: C₂₅H₃₃N₆O₉P

Purity: 99.99%

Color and Shape: Solid

Molecular weight: 592.54

Ref: TM-T41249