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CAS 37933-66-7

:

Thevetin A

Description:
Thevetin A is a toxic compound primarily derived from the seeds of the Thevetia peruviana plant, commonly known as the yellow oleander. It belongs to the class of cardiac glycosides, which are known for their ability to affect heart function. Thevetin A exhibits a structure characterized by a steroid nucleus with a sugar moiety, contributing to its biological activity. This compound is recognized for its potent cardiotoxic effects, which can lead to symptoms such as arrhythmias and gastrointestinal disturbances upon ingestion. Its mechanism of action involves the inhibition of the Na+/K+ ATPase enzyme, leading to increased intracellular sodium and calcium levels, ultimately affecting cardiac contractility. Due to its toxicity, Thevetin A is not used therapeutically and poses significant risks if consumed. Safety precautions are essential when handling this substance, as it can be lethal in small doses. Research continues to explore its potential applications in pharmacology, but its hazardous nature limits its practical use.
Formula:C42H64O19
InChI:InChI=1S/C42H64O19/c1-18-35(61-38-33(51)31(49)29(47)26(60-38)16-56-37-32(50)30(48)28(46)25(14-43)59-37)36(54-3)34(52)39(57-18)58-21-6-10-41(17-44)20(13-21)4-5-24-23(41)7-9-40(2)22(8-11-42(24,40)53)19-12-27(45)55-15-19/h12,17-18,20-26,28-39,43,46-53H,4-11,13-16H2,1-3H3/t18-,20+,21-,22+,23-,24+,25+,26+,28+,29+,30-,31-,32+,33+,34-,35-,36-,37+,38-,39-,40+,41+,42-/m0/s1
InChI key:InChIKey=WPNLWBRKPZXVGD-QMFRUYISSA-N
SMILES:C(=O)[C@@]12[C@@]3([C@]([C@]4(O)[C@](C)(CC3)[C@H](CC4)C=5COC(=O)C5)(CC[C@@]1(C[C@@H](O[C@H]6[C@@H](O)[C@H](OC)[C@@H](O[C@@H]7O[C@H](CO[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@H](O)[C@H](O)[C@H]7O)[C@H](C)O6)CC2)[H])[H])[H]
Synonyms:
  • (3beta,5beta)-3-((O-beta-D-glucopyranosyl-(1.6)-O-D-glucopyranosyl-(1.4)-6-deoxy-3-O-methyl-alpha-L-glucopyranosyl)oxy)-14-hydroxy-19-oxocard-20(22)-enolide
  • (3beta,5beta)-3-{[beta-D-glucopyranosyl-(1->6)-beta-D-glucopyranosyl-(1->4)-6-deoxy-3-O-methyl-alpha-L-glucopyranosyl]oxy}-14-hydroxy-19-oxocard-20(22)-enolide
  • (3β,5β)-3-[(O-β-<span class="text-smallcaps">D</smallcap>-Glucopyranosyl-(1→6)-O-β-<smallcap>D</smallcap>-glucopyranosyl-(1→4)-6-deoxy-3-O-methyl-α-<smallcap>L</span>-glucopyranosyl)oxy]-14-hydroxy-19-oxocard-20(22)-enolide
  • 3-{[hexopyranosyl-(1->6)hexopyranosyl-(1->4)-6-deoxy-3-O-methylhexopyranosyl]oxy}-14-hydroxy-19-oxocard-20(22)-enolide
  • 5-beta-Card-20(22)-enolide, 3-beta-((O-beta-D-glucopyranosyl-(1-6)-O-D-glucopyranosyl-(1-4)-6-deoxy-3-O-methyl-alpha-L-glucopyranosyl)oxy)-14-hydroxy-19-oxo-
  • Cannogenin + L-thevetose + 2-glucose
  • Cannogenin + L-thevetose + 2-glucose [German]
  • Card-20(22)-enolide, 3-[(O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-(1→6)-O-β-<smallcap>D</smallcap>-glucopyranosyl-(1→4)-6-deoxy-3-O-methyl-α-<smallcap>L</span>-glucopyranosyl)oxy]-14-hydroxy-19-oxo-, (3β,5β)-
  • Thevetin A
  • Card-20(22)-enolide, 3-[(O-β-D-glucopyranosyl-(1→6)-O-β-D-glucopyranosyl-(1→4)-6-deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-19-oxo-, (3β,5β)-
  • (3β,5β)-3-[(O-β-D-Glucopyranosyl-(1→6)-O-β-D-glucopyranosyl-(1→4)-6-deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-19-oxocard-20(22)-enolide
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Found 4 products.
  • Thevetin A
    Glentham
    + Info

    Thevetin A

    CAS:
    Formula:C42H64O19
    Molecular weight:872.95

    Ref: 7W-GL2522

    ne
    To inquire
  • Thevetin A
    Biopurify
    + Info

    Thevetin A

    CAS:
    Formula:C42H64O19
    Purity:95%~99%
    Molecular weight:872.955

    Ref: BP-BP4809

    5mg
    730.00€
  • Thevetin A
    Targetmol
    + Info

    Thevetin A

    CAS:
    <p>Thevetin A is a useful organic compound for research related to life sciences. The catalog number is T124930 and the CAS number is 37933-66-7.</p>
    Formula:C42H64O19
    Color and Shape:Solid
    Molecular weight:872.955

    Ref: TM-T124930

  • Thevetin A
    Biosynth
    + Info

    Thevetin A

    CAS:
    Thevetin A is an extract from the cascabela tree that contains hydroxy groups. This extract has been shown to have a potent effect in clinical studies as a control agent for congestive heart failure. Thevetin A has also been shown to be effective in treating trigeminal neuralgia and cardiac effects. It is believed that it may be due to its ability to increase the release of norepinephrine and serotonin, which are neurotransmitters that affect pain perception and mood.
    Formula:C42H64O19
    Purity:Min. 95%
    Molecular weight:872.9 g/mol

    Ref: 3D-MBA93366

    1mg
    863.00€
    2mg
    1,036.00€
    5mg
    2,112.00€