CAS 38092-89-6
:N-Methyldesloratadine
Description:
N-Methyldesloratadine is a chemical compound that serves as an active metabolite of desloratadine, which is an antihistamine used primarily for the treatment of allergic symptoms. It is characterized by its ability to selectively antagonize peripheral H1 histamine receptors, thereby alleviating symptoms such as sneezing, runny nose, and itchy eyes associated with allergic rhinitis. The compound is known for its low sedative properties, making it suitable for use in non-drowsy formulations. N-Methyldesloratadine is typically administered orally and exhibits a favorable pharmacokinetic profile, including good bioavailability and a relatively long half-life, allowing for once-daily dosing. Its chemical structure includes a piperidine ring and a methyl group, contributing to its pharmacological activity. Additionally, it is generally well-tolerated, with a low incidence of side effects compared to first-generation antihistamines. As with any medication, it is important to consider potential interactions and contraindications when prescribing or using N-Methyldesloratadine.
Formula:C20H21ClN2
InChI:InChI=1/C20H21ClN2/c1-23-11-8-14(9-12-23)19-18-7-6-17(21)13-16(18)5-4-15-3-2-10-22-20(15)19/h2-3,6-7,10,13H,4-5,8-9,11-12H2,1H3
InChI key:InChIKey=VLXSCTINYKDTKR-UHFFFAOYSA-N
SMILES:ClC=1C=C2C(C(C=3C(CC2)=CC=CN3)=C4CCN(C)CC4)=CC1
Synonyms:- 5H-benzo[5,6]cyclohepta[1,2-b]pyridine, 8-chloro-6,11-dihydro-11-(1-methyl-4-piperidinylidene)-
- 8-Chloro-11-(1-methyl-4-piperidinylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
- 8-Chloro-11-(1-methylpiperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
- Methyl loratadine
- N-Methyldesloratadine
- 8-Chloro-6,11-dihydro-11-(1-methyl-4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
- 6,11ihydro-5H-Benzo-5,6Cyclohepta-L,2-BPyridine,Loratadine
- 8-Chloro-11-(1-Methyl-4-Piperidinylidene)-6, 11-dihydro 5H-Benzo [5,6] cyclohepta (1,2-b) Pyridine
- 8-CHLORO-11-(1-METHYL-4-PIPERIDINYLIDENE-6,11-DIHYDRO-5H-BNZO[5.6])CYCLOHEPTA[1,2-B]PYRIDINE
- 8-chloro-11-(1-methyl-4-piperidylidenel-5,11)-dihydro-5H-benzo5,6-cyclohepta
- 8-CHLORO-11-(L-METHYL-4-PIPERIDINYLIDENE-6,11-DIHYDRO-5H-BENZO[5.6])CYCLOHEPTA[L,2-B]PYRIDINE
- 8-CHLORO-6,11-DIHYDRO-11-(1-METHYL-4-PIPERIDINYLIDENE)-5H-BENZO[5,6] CYCLOHEPTA [1,2-B]PYRIDINE =99%
- 8-CHLORO AZATADINE
- 8-CHLORO-5,6-DIHYDRO-11H-BENZO[5,6]CYCLOHEPTO[1,2-B]PYRIDINE-11-ONE
- 8-CHLORO-11-(1-METHYL-4-PIPERIDYLIDENE)-6,11-DIHYDRO-5H-BENZO(5,6)CYCLOHEPTAL[1,2-B]PYRIDINE
- 8-chloro-11-(1-methyl-4-piperidylidenel-5,11)-dihydro-5H-benzo〔5,6〕-cyclohepta〔1,2-b〕pyridine
- 8-Chloro-11-(1-Methyl-4-Piperidylidene-5,11)-Dihydro-5h-Benzo(5,6)Cycloheptal[1,2-B]Pyridine
- 8-Chloro-11-(1-Methyl-4-Piperidylidene-5,11)-Dihydro-5h-Benzo(5,6)Cyclohepta[1,2-B]Pyridine
- 6,11 –Dihydro-5H-Benzo-5,6Cyclohepta-L,2-B Pyridine, Loratadine,
- See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 10 products.
Loratadine Related Compound B (8-Chloro-5,6-dihydro-11-(N-methylpiperidin-4-ylidene)-11H-benzo[5,6]cyclohepta[1,2-b]pyridine)
CAS:Compounds containing an unfused pyridine ring in the structure, nesoiFormula:C20H21ClN2Color and Shape:White Crystalline PowderMolecular weight:324.139338-chloro-11-(1-methylpiperidin-4-ylidene)-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridine
CAS:Formula:C20H21ClN2Purity:97%Color and Shape:SolidMolecular weight:324.8471Loratadine EP Impurity G (Loratadine USP Related Compound B, Methyl Loratadine)
CAS:Formula:C20H21ClN2Color and Shape:Off-White SolidMolecular weight:324.858-Chloro-11-[(n-methyl)-4-piperidylidene]-6,11-dihydro-5h-benzo [5,6] cyclohepta[1,2b]pyridine
CAS:8-Chloro-11-[(n-methyl)-4-piperidylidene]-6,11-dihydro-5h-benzo [5,6] cyclohepta[1,2b]pyridineFormula:C20H21ClN2Purity:97%Color and Shape: white powderMolecular weight:324.85g/mol8-Chloro-11-(1-methylpiperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
CAS:Controlled ProductFormula:C20H21ClN2Color and Shape:NeatMolecular weight:324.85N-Methyl Desloratadine
CAS:Controlled ProductFormula:C20H21ClN2Color and Shape:Off-WhiteMolecular weight:324.85N-Methyl desloratadine
CAS:<p>N-Methyl desloratadine is a molecule that is used as a template molecule for the preparation of samples. It is often used to measure the efficiency of extraction methods, such as high-performance liquid chromatography (HPLC) and gas chromatography (GC). The sample preparation process can be completed in less than one hour and requires only small amounts of reagents. N-Methyl desloratadine has been shown to be useful in detecting environmental pollution, such as diode, systematically. It also has been used to measure plasma levels of sodium citrate in human blood.</p>Formula:C20H21ClN2Purity:Min. 95%Molecular weight:324.85 g/molN-Methyl Desloratadine
CAS:N-Methyl Desloratadine is a useful organic compound for research related to life sciences. The catalog number is T65952 and the CAS number is 38092-89-6.Formula:C20H21ClN2Color and Shape:SolidMolecular weight:324.85
![8-chloro-11-(1-methylpiperidin-4-ylidene)-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA00I7I7.jpg&w=3840&q=75)
![8-Chloro-11-[(n-methyl)-4-piperidylidene]-6,11-dihydro-5h-benzo [5,6] cyclohepta[1,2b]pyridine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F54%2Fthumb%2FOR345568.jpg&w=3840&q=75)
![8-Chloro-11-(1-methylpiperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F86%2Fthumb%2FMM0257.05.jpg&w=3840&q=75)
