CAS 38092-89-6: N-Methyldesloratadine

Description: N-Methyldesloratadine is a chemical compound that serves as an active metabolite of desloratadine, which is an antihistamine used primarily for the treatment of allergic symptoms. It is characterized by its ability to selectively antagonize peripheral H1 histamine receptors, thereby alleviating symptoms such as sneezing, runny nose, and itchy eyes associated with allergic rhinitis. The compound is known for its low sedative properties, making it suitable for use in non-drowsy formulations. N-Methyldesloratadine is typically administered orally and exhibits a favorable pharmacokinetic profile, including good bioavailability and a relatively long half-life, allowing for once-daily dosing. Its chemical structure includes a piperidine ring and a methyl group, contributing to its pharmacological activity. Additionally, it is generally well-tolerated, with a low incidence of side effects compared to first-generation antihistamines. As with any medication, it is important to consider potential interactions and contraindications when prescribing or using N-Methyldesloratadine.

Formula: C₂₀H₂₁ClN₂

InChI: InChI=1S/C20H21ClN2/c1-23-11-8-14(9-12-23)19-18-7-6-17(21)13-16(18)5-4-15-3-2-10-22-20(15)19/h2-3,6-7,10,13H,4-5,8-9,11-12H2,1H3

InChI key: InChIKey=VLXSCTINYKDTKR-UHFFFAOYSA-N

SMILES: ClC=1C=CC2=C(C1)CCC=3C=CC=NC3C2=C4CCN(C)CC4

Synonyms:

• 5H-benzo[5,6]cyclohepta[1,2-b]pyridine, 8-chloro-6,11-dihydro-11-(1-methyl-4-piperidinylidene)-
• 8-Chloro-11-(1-methyl-4-piperidinylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
• 8-Chloro-11-(1-methylpiperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
• Methyl loratadine
• N-Methyldesloratadine
• 8-Chloro-6,11-dihydro-11-(1-methyl-4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine

Loratadine Related Compound B (8-Chloro-5,6-dihydro-11-(N-methylpiperidin-4-ylidene)-11H-benzo[5,6]cyclohepta[1,2-b]pyridine)

CAS: 38092-89-6

Compounds containing an unfused pyridine ring in the structure, nesoi

• Formula: C₂₀H₂₁ClN₂
• Color and Shape: White Crystalline Powder
• Molecular weight: 324.13933

8-chloro-11-(1-methylpiperidin-4-ylidene)-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridine

CAS: 38092-89-6

• Formula: C₂₀H₂₁ClN₂
• Purity: 97%
• Color and Shape: Solid
• Molecular weight: 324.8471

Loratadine EP Impurity G (Loratadine USP Related Compound B, Methyl Loratadine)

CAS: 38092-89-6

• Formula: C₂₀H₂₁ClN₂
• Color and Shape: Off-White Solid
• Molecular weight: 324.85

8-Chloro-11-[(n-methyl)-4-piperidylidene]-6,11-dihydro-5h-benzo [5,6] cyclohepta[1,2b]pyridine

CAS: 38092-89-6

• Formula: C₂₀H₂₁ClN₂
• Purity: 97%
• Color and Shape: white powder
• Molecular weight: 324.85g/mol

N-Methyl Desloratadine

CAS: 38092-89-6

N-Methyl Desloratadine is a useful organic compound for research related to life sciences. The catalog …

• Formula: C₂₀H₂₁ClN₂
• Color and Shape: Liquid
• Molecular weight: 324.85

8-Chloro-11-(1-methylpiperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine

CAS: 38092-89-6

• Formula: C₂₀H₂₁ClN₂
• Color and Shape: Neat
• Molecular weight: 324.85

N-Methyl Desloratadine

CAS: 38092-89-6

• Formula: C₂₀H₂₁ClN₂
• Color and Shape: Off-White
• Molecular weight: 324.85

N-Methyl desloratadine

CAS: 38092-89-6

Please enquire for more information about N-Methyl desloratadine including the price, delivery time and more …

• Formula: C₂₀H₂₁ClN₂
• Purity: Min. 95%
• Molecular weight: 324.85 g/mol

8-Chloroazatadine

CAS: 38092-89-6

• Purity: 97%
• Molecular weight: 324.8500061035156