CAS 38092-95-4

Desloratadine Impurity 9 (N-Desmethyl Azatadine)

CAS: 38092-95-4

Formula: C₁₉H₂₀N₂

Color and Shape: White To Off-White Solid

Molecular weight: 276.38

Ref: 4Z-L-1034

Dechloro desloratadine

CAS: 38092-95-4

Formula: C₁₉H₂₀N₂

Molecular weight: 276.4

Ref: ST-EA-CP-D15008

N-Desmethyl Azatadine

CAS: 38092-95-4

Applications N-Desmethyl Azatadine is a minor metabolite of Azatadine Dimaleate (A802950); an antihistamine.
References Ma, C., et al.: J. Pharm. Biomed. Anal., 47, 677 (2008); De Graw, A., et al.: J. Med. Chem., 53, 2464 (2010); Dresen, S., et al.: Anal. Bioanal. Chem., 396, 2425 (2010); Zhang, D., et al.: Appl. Environ. Microb., 62, 3477 (1996)

Formula: C₁₉H₂₀N₂

Color and Shape: Neat

Molecular weight: 276.3755

Ref: TR-D290940

N-Desmethyl azatadine

CAS: 38092-95-4

N-Desmethyl azatadine is a piperidinecarboxylic acid, which is an active metabolite of the antihistamine loratadine and the decongestant azatadine. It is used in the treatment of chronic cough associated with reflux. N-Desmethyl azatadine has been shown to be effective in reducing symptoms of chronic cough in patients with gastroesophageal reflux disease (GERD) or symptomatic GERD. This drug binds to histamine H1 receptors, inhibiting histamine binding and blocking its effects on the body. N-Desmethyl azatadine also inhibits the production of acid by bacteria in the stomach, decreasing acidity and improving symptoms of GERD.

Formula: C₁₉H₂₀N₂

Purity: 90% Min

Molecular weight: 276.38 g/mol

Ref: 3D-NBA09295