CAS 3810-80-8: Diphenoxylate hydrochloride
Description:Diphenoxylate hydrochloride is a synthetic opioid used primarily as an antidiarrheal agent. It functions by slowing down gut motility, thereby reducing the frequency of bowel movements and alleviating diarrhea. The substance is a white to off-white crystalline powder that is soluble in water and alcohol, making it suitable for various pharmaceutical formulations. Its mechanism of action involves binding to opioid receptors in the gastrointestinal tract, which decreases peristalsis and increases the time substances remain in the intestines. Diphenoxylate is often combined with atropine to discourage misuse and potential abuse, as the combination can produce unpleasant side effects when taken in higher doses. While effective for treating diarrhea, it is important to use diphenoxylate hydrochloride under medical supervision due to potential side effects, including constipation, dizziness, and drowsiness. Additionally, caution is advised in patients with certain medical conditions, such as liver disease or a history of substance abuse. Overall, diphenoxylate hydrochloride is a valuable medication in managing diarrhea when used appropriately.
Formula:C30H32N2O2·ClH
InChI:InChI=1S/C30H32N2O2.ClH/c1-2-34-28(33)29(25-12-6-3-7-13-25)18-21-32(22-19-29)23-20-30(24-31,26-14-8-4-9-15-26)27-16-10-5-11-17-27;/h3-17H,2,18-23H2,1H3;1H
InChI key:InChIKey=SHTAFWKOISOCBI-UHFFFAOYSA-N
SMILES:Cl.N#CC(C=1C=CC=CC1)(C=2C=CC=CC2)CCN3CCC(C(=O)OCC)(C=4C=CC=CC4)CC3
- Synonyms:
- 1-(3-Cyano-3,3-Diphenylpropyl)-4-(Ethoxycarbonyl)-4-Phenylpiperidinium Chloride
- 1-(3-Cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylic acid ethyl ester hydrochloride
- 2,2-Diphenyl-4-(4-carbethoxy-4-phenyl-1-piperidino)butyronitrile hydrochloride
- 2,2-Diphenyl-4-(4-carboxy-4-phenyl-1-piperidino)butyronitrile ethyl ester hydrochloride
- 4-Piperidinecarboxylic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethyl ester, hydrochloride (1:1)
- 4-Piperidinecarboxylic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethyl ester, monohydrochloride
- Diphenoxylate HCL (Subj To Narcotic Permit)
- Isonipecotic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethyl ester, hydrochloride
- Isonipecotic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethyl ester, monohydrochloride
- R 1132
- See more synonyms
- R 1132 (antiperistaltic)
