CAS 3810-80-8

Diphenoxylate hydrochloride

Description:

Diphenoxylate hydrochloride is a synthetic opioid used primarily as an antidiarrheal agent. It functions by slowing down gut motility, thereby reducing the frequency of bowel movements and alleviating diarrhea. The substance is a white to off-white crystalline powder that is soluble in water and alcohol, making it suitable for various pharmaceutical formulations. Its mechanism of action involves binding to opioid receptors in the gastrointestinal tract, which decreases peristalsis and increases the time substances remain in the intestines. Diphenoxylate is often combined with atropine to discourage misuse and potential abuse, as the combination can produce unpleasant side effects when taken in higher doses. While effective for treating diarrhea, it is important to use diphenoxylate hydrochloride under medical supervision due to potential side effects, including constipation, dizziness, and drowsiness. Additionally, caution is advised in patients with certain medical conditions, such as liver disease or a history of substance abuse. Overall, diphenoxylate hydrochloride is a valuable medication in managing diarrhea when used appropriately.

Formula:C₃₀H₃₂N₂O₂·ClH

InChI:InChI=1S/C30H32N2O2.ClH/c1-2-34-28(33)29(25-12-6-3-7-13-25)18-21-32(22-19-29)23-20-30(24-31,26-14-8-4-9-15-26)27-16-10-5-11-17-27;/h3-17H,2,18-23H2,1H3;1H

InChI key:InChIKey=SHTAFWKOISOCBI-UHFFFAOYSA-N

SMILES:C(CCN1CCC(C(OCC)=O)(CC1)C2=CC=CC=C2)(C#N)(C3=CC=CC=C3)C4=CC=CC=C4.Cl

Synonyms:

1-(3-Cyano-3,3-Diphenylpropyl)-4-(Ethoxycarbonyl)-4-Phenylpiperidinium Chloride
1-(3-Cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylic acid ethyl ester hydrochloride
2,2-Diphenyl-4-(4-carbethoxy-4-phenyl-1-piperidino)butyronitrile hydrochloride
2,2-Diphenyl-4-(4-carboxy-4-phenyl-1-piperidino)butyronitrile ethyl ester hydrochloride
4-Piperidinecarboxylic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethyl ester, hydrochloride (1:1)
4-Piperidinecarboxylic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethyl ester, monohydrochloride
Diphenoxylate HCL (Subj To Narcotic Permit)
Isonipecotic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethyl ester, hydrochloride
Isonipecotic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethyl ester, monohydrochloride
R 1132
R 1132 (antiperistaltic)

Purity (%)

100

Found 8 products.

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Diphenoxylate Hydrochloride
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 3810-80-8
Color and Shape:Neat
Ref: 61-FOR1056.00
10mg
314.00€
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Diphenoxylate Hydrochloride
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 3810-80-8
Formula:C₃₀H₃₂N₂O₂·ClH
Color and Shape:Neat
Molecular weight:489.05
Ref: 86-MM1056.00
250mg
1,471.00€
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Diphenoxylate Hydrochloride
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 3810-80-8
Applications Antiperistaltic; antidiarrheal. Controlled substance (opiate). Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Karim, et al.: J. Pharmacol. Exp. Ther., 177, 546 (1971), Hung, D.D., et al.: Anal. Profiles Drug Subs., 7, 149 (1978), 
Formula:C₃₀H₃₂N₂O₂·ClH
Color and Shape:Neat
Molecular weight:489.05
Ref: TR-D489400
5mg
280.00€
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50mg
1,918.00€
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Diphenoxylate Hydrochloride (1.0mg/ml in Acetonitrile)
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 3810-80-8
Formula:C₃₀H₃₂N₂O₂·ClH
Color and Shape:Colourless
Molecular weight:489.05
Ref: TR-KIT4440
5x1ml
1,027.00€
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DIPHENOXYLATE HYDROCHLORIDE CRS - * NARC
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 3810-80-8
DIPHENOXYLATE HYDROCHLORIDE CRS - * NARC
Formula:C₃₀H₃₃ClN₂O₂
Color and Shape:Crystalline Powder. White. Powder.
Molecular weight:489.0482
Ref: 41-Y0001415
15mg
115.00€
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DIPHENOXYLATE FOR SYSTEM SUITABILITY CRS - * NARC
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 3810-80-8
DIPHENOXYLATE FOR SYSTEM SUITABILITY CRS - * NARC
Formula:C₃₀H₃₃ClN₂O₂
Molecular weight:489.0482
Ref: 41-Y0001430
10mg
115.00€
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Diphenoxylate Hydrochloride CII
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 3810-80-8
Alfentanil (inn), anileridine (inn), bezitramide (inn), bromazepam (inn), difenoxin (inn), diphenoxylate (inn), dipipanone (inn), fentanyl (inn), etc.
Formula:C₃₀H₃₂N₂O₂·ClH
Color and Shape:White Crystalline Powder
Molecular weight:489.05
Ref: 45-1219008
+ Info
Diphenoxylate hydrochloride
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 3810-80-8
Diphenoxylate hydrochloride is a drug that belongs to the class of nonsteroidal anti-inflammatory drugs. It is used for the treatment of bowel disease, such as irritable bowel syndrome and ulcerative colitis. It also has been used in the treatment of infectious diseases, such as bacterial infections, malaria, amebic dysentery, giardiasis, and shigellosis. Diphenoxylate hydrochloride inhibits the production of prostaglandins by inhibiting cyclooxygenase activity. It also binds to cell factor and antibiotic agents, which may be due to its polymerase chain reaction (PCR) properties. Diphenoxylate hydrochloride should not be taken with vancomycin hydrochloride because they are both metabolized by cytochrome P450 enzymes and can cause drug interactions.
Formula:C₃₀H₃₂N₂O₂·HCl
Purity:Min. 95%
Color and Shape:Powder
Molecular weight:489.05 g/mol
Ref: 3D-FD65006
250mg
1,962.00€
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