CAS 3811-25-4

Clorprenaline

Description:

Clorprenaline, with the CAS number 3811-25-4, is a synthetic compound classified as a beta-adrenergic agonist. It primarily acts on beta-2 adrenergic receptors, leading to bronchodilation and relaxation of smooth muscle, making it useful in treating respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). Clorprenaline is known for its ability to stimulate the heart and increase heart rate, although its primary therapeutic application is in the respiratory system. The compound is typically administered via inhalation or oral routes, depending on the formulation. In addition to its bronchodilator effects, Clorprenaline may exhibit anti-inflammatory properties, contributing to its efficacy in managing respiratory disorders. As with many beta-agonists, potential side effects can include tachycardia, tremors, and nervousness, particularly at higher doses. Its use is regulated in various countries, especially in veterinary medicine, where it is sometimes employed to enhance performance in livestock. Overall, Clorprenaline is a significant agent in the pharmacological management of airway diseases.

Formula: C₁₁H₁₆ClNO

InChI: InChI=1S/C11H16ClNO/c1-8(2)13-7-11(14)9-5-3-4-6-10(9)12/h3-6,8,11,13-14H,7H2,1-2H3

InChI key: InChIKey=SSMSBSWKLKKXGG-UHFFFAOYSA-N

SMILES: C(CNC(C)C)(O)C1=C(Cl)C=CC=C1

Synonyms:

• (±)-Chloroprenaline
• 1-(2-Chlorophenyl)-2-(Propan-2-Ylamino)Ethanol
• 1-(2-Chlorophenyl)-2-Isopropylaminoethanol
• 1-(2-Chlorophenyl)-2-[(propan-2-yl)amino]ethan-1-ol
• 1-o-Chlorophenyl-2-isopropylaminoethanol
• 2-Chloro-α-[(isopropylamino)methyl]benzenemethanol
• 2-Chloro-α-[[(1-methylethyl)amino]methyl]benzenemethanol
• Benzenemethanol, 2-chloro-α-[[(1-methylethyl)amino]methyl]-
• Benzyl alcohol, o-chloro-α-[(isopropylamino)methyl]-
• E 241
• Isoprofenamine
• Isoprophenamine
• o-Chloro-α-(isopropylaminomethyl)benzyl alcohol

1-(2-chlorophenyl)-2-[(propan-2-yl)amino]ethan-1-ol

CAS: 3811-25-4

Formula: C₁₁H₁₆ClNO

Purity: 98%

Molecular weight: 213.7038

Ref: IN-DA00ILQA

Clorprenaline 100 µg/mL in Acetonitrile

CAS: 3811-25-4

Formula: C₁₁H₁₆ClNO

Color and Shape: Single Solution

Molecular weight: 213.70

Ref: 04-A11687500AL-100

Clorprenaline

CAS: 3811-25-4

Clorprenaline is a β-adrenergic receptor agonist that activates adenylate cyclase, relaxation of bronchial smooth muscle cells. anti-inflammatory.

Formula: C₁₁H₁₆ClNO

Purity: 98.9%

Color and Shape: Solid

Molecular weight: 213.7

Ref: TM-T60261

(±)-Clorprenaline-d7 (iso-propyl-d7)

Controlled Product

CAS: 3811-25-4

Applications (±)-Clorprenaline-d7 (iso-propyl-d7) is a useful isotopically labeled compound of Clorprenaline (C587150)

Formula: C₁₁₂H₇H₉ClNO

Color and Shape: Neat

Molecular weight: 220.75

Ref: TR-C587152

Clorprenaline Hydrochloride-D7

Controlled Product

CAS: 3811-25-4, 6933-90-0

Stability Hygroscopic
Applications Clorprenaline Hydrochloride-D7 is an isotopically labeled form of Clorprenaline Hydrochloride (C427955). Clorprenaline Hydrochloride is a beta-adrenergic blocking agent.
References Zhou, S., et al.: Elctrophoresis, 29, 321 (2008);

Formula: C₁₁H₉D₇ClNO•HCl

Color and Shape: Neat

Molecular weight: 257.21

Ref: TR-C427957

Clorprenaline

CAS: 3811-25-4

Clorprenaline is a sympathomimetic drug that binds to and activates the beta-adrenergic receptors, which are found in the heart, lungs, kidneys and other tissues. Clorprenaline is used as a bronchodilator in chronic pulmonary diseases such as asthma. It has also been used as a cardiac stimulant and an antihypertensive agent. Clorprenaline has been shown to be a good absorption enhancer for drugs with poor bioavailability. The hydroxyl group on clorprenaline reacts with fatty acids to form esters. These reactions can be monitored by gas chromatography with flame ionization detection (GC-FID) or high-performance liquid chromatography (HPLC). A monoclonal antibody was used for the detection sensitivity of clorprenaline in plasma samples from patients with chronic lung disease who were administered clorprenaline via inhalation therapy. Sodium citrate is often added to the sample buffer because it increases the

Formula: C₁₁H₁₆ClNO

Purity: Min. 95%

Molecular weight: 213.7 g/mol

Ref: 3D-DAA81125