CAS 381683-92-7

4-{2-[5-chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1H-indol-3-yl]ethoxy}benzoic acid

Description:

The chemical substance known as 4-{2-[5-chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1H-indol-3-yl]ethoxy}benzoic acid, with the CAS number 381683-92-7, is a complex organic compound characterized by its intricate molecular structure. It features multiple functional groups, including a benzoic acid moiety, an indole ring, and a sulfonamide linkage, which contribute to its potential biological activity. The presence of chlorine atoms suggests that it may exhibit specific reactivity or biological interactions, potentially influencing its pharmacological properties. This compound is likely to be of interest in medicinal chemistry, particularly in the development of therapeutic agents, due to its structural complexity and the presence of various substituents that can affect its solubility, stability, and interaction with biological targets. As with many synthetic organic compounds, its properties, such as solubility, melting point, and biological activity, would need to be characterized through experimental studies to fully understand its potential applications.

Formula: C₃₉H₃₃Cl₃N₂O₅S

InChI: InChI=1/C39H33Cl3N2O5S/c40-30-14-18-36-33(24-30)32(20-22-49-31-15-12-29(13-16-31)39(45)46)37(19-21-43-50(47,48)25-26-11-17-34(41)35(42)23-26)44(36)38(27-7-3-1-4-8-27)28-9-5-2-6-10-28/h1-18,23-24,38,43H,19-22,25H2,(H,45,46)

SMILES: c1ccc(cc1)C(c1ccccc1)n1c2ccc(cc2c(CCOc2ccc(cc2)C(=O)O)c1CCNS(=O)(=O)Cc1ccc(c(c1)Cl)Cl)Cl

Synonyms:

• benzoic acid, 4-[2-[5-chloro-2-[2-[[[(3,4-dichlorophenyl)methyl]sulfonyl]amino]ethyl]-1-(diphenylmethyl)-1H-indol-3-yl]ethoxy]-

Ecopladib

CAS: 381683-92-7

Ecopladib

Purity: ≥95%

Molecular weight: 748.11g/mol

Ref: 54-BUP12836

Ecopladib

CAS: 381683-92-7

Ecopladib (also known as EC-P) is a novel synthetic compound that is a potent metalloprotease inhibitor. This drug is most effective in inhibiting the activity of serine proteases, such as plasmin and cathepsin B. Ecopladib has shown efficacy in animal models of acute renal injury, with its antiinflammatory activity being mediated by its ability to block the production of inflammatory cytokines. This drug also protects against acute kidney injury through its inhibition of the activity of c1-6 alkyl groups.

Formula: C₃₉H₃₃Cl₃N₂O₅S

Purity: Min. 95%

Molecular weight: 748.1 g/mol

Ref: 3D-GQA68392

Ecopladib

CAS: 381683-92-7

Ecopladib inhibits cPLA2α with IC50 of 0.15 μM (micelles) & 0.11 μM (rat blood).

Formula: C₃₉H₃₃Cl₃N₂O₅S

Purity: 95.15%

Color and Shape: Solid

Molecular weight: 748.11

Ref: TM-T11149