CAS 382-52-5

(6alpha,11beta)-9-fluoro-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione

Description:

The chemical substance known as (6alpha,11beta)-9-fluoro-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione, with the CAS number 382-52-5, is a synthetic corticosteroid commonly referred to as dexamethasone. It exhibits potent anti-inflammatory and immunosuppressive properties, making it widely used in medical applications to treat various conditions, including allergies, autoimmune disorders, and certain types of cancer. Dexamethasone functions by mimicking the effects of cortisol, a natural hormone produced by the adrenal glands, and it works by binding to glucocorticoid receptors, influencing gene expression and modulating inflammatory responses. The compound is characterized by its fluorinated structure, which enhances its biological activity and stability. Dexamethasone is typically administered orally, intravenously, or intramuscularly, and its pharmacokinetics include rapid absorption and a relatively long half-life, allowing for effective management of symptoms. However, its use can be associated with side effects, particularly with long-term administration, necessitating careful monitoring by healthcare professionals.

Formula: C₂₂H₂₉FO₅

InChI: InChI=1/C22H29FO5/c1-12-8-16-14-5-7-21(28,18(27)11-24)20(14,3)10-17(26)22(16,23)19(2)6-4-13(25)9-15(12)19/h4,6,9,12,14,16-17,24,26,28H,5,7-8,10-11H2,1-3H3/t12-,14-,16-,17-,19-,20-,21-,22-/m0/s1

SMILES: C[C@H]1C[C@H]2[C@@H]3CC[C@](C(=O)CO)([C@@]3(C)C[C@@H]([C@@]2([C@@]2(C)C=CC(=O)C=C12)F)O)O

Synonyms:

• 9alpha-Fluoro-11beta,17alpha,21-trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-6-methyl-, (6.alpha.,11.beta.)-

Fluorometholone Impurity 6

CAS: 382-52-5

Formula: C₂₂H₂₉FO₅

Color and Shape: White To Off-White Solid

Molecular weight: 392.47

Ref: 4Z-F-6413

9α-Fluoro-6α-methylprednisolone

Controlled Product

CAS: 382-52-5

Formula: C₂₂H₂₉FO₅

Color and Shape: Neat

Molecular weight: 392.461

Ref: TR-F596115

Fluorometholone 21-hydroxy analogue

Controlled Product

CAS: 382-52-5

Fluorometholone 21-hydroxy analogue is a drug product that is custom synthesized for a specific customer. The drug has high purity and analytical data are available. Metabolism studies have been performed on the drug, and it is natural. Drug development and pharmacopoeia are also available for this drug. Metabolite, impurity standard, research and development, HPLC standard are all available for this drug.

Formula: C₂₂H₂₉FO₅

Purity: Min. 95%

Molecular weight: 392.46 g/mol

Ref: 3D-FF168679

Fluorometholone Impurity 1

CAS: 382-52-5

Formula: C₂₂H₂₉FO₅

Molecular weight: 392.5

Ref: ST-EA-CP-F31001