CAS 38275-34-2

4-Pyrimidinecarboxylicacid, 5-chloro-2-(methylsulfonyl)-

Description:

4-Pyrimidinecarboxylic acid, 5-chloro-2-(methylsulfonyl)-, identified by CAS number 38275-34-2, is a chemical compound that features a pyrimidine ring substituted with a carboxylic acid group and a chloro group, along with a methylsulfonyl moiety. This compound is characterized by its heterocyclic structure, which contributes to its potential biological activity. The presence of the carboxylic acid group indicates that it can participate in acid-base reactions, while the chloro substituent may influence its reactivity and interaction with biological targets. The methylsulfonyl group enhances its solubility in polar solvents and may also play a role in its pharmacological properties. This compound is of interest in medicinal chemistry and may be explored for its potential applications in pharmaceuticals, particularly in the development of agents targeting specific biological pathways. Its synthesis and characterization involve standard organic chemistry techniques, and it is essential to handle it with care due to the presence of the chloro substituent, which can impart toxicity.

Formula: C₆H₅ClN₂O₄S

Synonyms:

• 5-Chloro-2-(methylsulfonyl)-4-pyrimidinecarboxylicacid

5-Chloro-2-(methylsulfonyl)pyrimidine-4-carboxylic acid

CAS: 38275-34-2

Formula: C₆H₅ClN₂O₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 236.6329

Ref: IN-DA00CM5D

PK11000

CAS: 38275-34-2

PK11000

Purity: ≥98%

Molecular weight: 236.63g/mol

Ref: 54-BUP06021

5-Chloro-2-methanesulfonyl-pyrimidine-4-carboxylic acid

CAS: 38275-34-2

5-Chloro-2-methanesulfonyl-pyrimidine-4-carboxylic acid

Purity: 95%

Molecular weight: 236.64g/mol

Ref: 54-OR97395

PK11000

CAS: 38275-34-2

PK11000 is a p53 targeting compound, has anti-tumor activities through activation of unstable p53.

Formula: C₆H₅ClN₂O₄S

Purity: 99.70%

Color and Shape: Solid

Molecular weight: 236.63

Ref: TM-T4459

5-Chloro-2-(methylsulfonyl)pyrimidine-4-carboxylic acid

CAS: 38275-34-2

Formula: C₆H₅ClN₂O₄S

Purity: 97%

Color and Shape: Liquid, No data available.

Molecular weight: 236.63

Ref: 10-F234165

PK11007

CAS: 38275-34-2

PK11007 is a novel anticancer drug that has been shown to have an anti-cancer effect on breast cancer cell lines. PK11007 binds to DNA and inhibits the transcriptional regulation of genes. It also has been shown to be a predictive biomarker for prognosis, as well as being sensitive to changes in cellular environment. This drug is synthesized from the secondary metabolite dibenzo[a,j]pyrene-7,8-diol, which is found in Astragalus membranaceus. The synthesis method involves the use of palladium catalyzed reductive amination and oxidation of dibenzo[a,j]pyrene-7,8-diol with sodium sulfide.

Formula: C₆H₅ClN₂O₄S

Purity: Min. 95%

Molecular weight: 236.63 g/mol

Ref: 3D-NBA27534