CAS 3828-96-4

5-fluorouridine 5'-(tetrahydrogen triphosphate)

Description:

5-Fluorouridine 5'-(tetrahydrogen triphosphate), commonly referred to as 5-FUTP, is a nucleotide analog of uridine triphosphate (UTP) where the uracil base is substituted with a fluorine atom at the 5-position. This modification imparts unique biochemical properties, making it a valuable tool in molecular biology and biochemistry. 5-FUTP is involved in RNA synthesis and can be incorporated into RNA molecules, potentially affecting their stability and function. The presence of the fluorine atom can alter the hydrogen bonding patterns and base pairing properties, which may influence the activity of RNA-dependent processes. Additionally, 5-FUTP can serve as a substrate for various enzymes, including RNA polymerases, and is often used in studies related to RNA metabolism and antiviral research. Its CAS number, 3828-96-4, identifies it in chemical databases, facilitating its procurement and study. Overall, 5-fluorouridine 5'-(tetrahydrogen triphosphate) is a significant compound in the field of nucleic acid research and therapeutic development.

Formula: C₉H₁₄FN₂O₁₅P₃

InChI: InChI=1/C9H14FN2O15P3/c10-3-1-12(9(16)11-7(3)15)8-6(14)5(13)4(25-8)2-24-29(20,21)27-30(22,23)26-28(17,18)19/h1,4-6,8,13-14H,2H2,(H,20,21)(H,22,23)(H,11,15,16)(H2,17,18,19)/t4-,5-,6-,8?/m1/s1

SMILES: c1c(c(nc(=O)n1C1[C@@H]([C@@H]([C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O1)O)O)O)F

5-Fluorouridine-5'-triphosphate sodium salt

CAS: 3828-96-4

5-Fluorouridine-5'-triphosphate sodium salt is an analog of uridine that has been used in the treatment of metastatic colorectal cancer. It is a prodrug that is metabolized to 5-fluorouracil, its active form. 5-Fluorouridine-5'-triphosphate sodium salt inhibits the synthesis of thymidylate, one of the precursors to DNA, and blocks the production of nucleotides. This results in cell lysis and death by apoptosis. The drug also inhibits epidermal growth factor receptor (EGFR), which may contribute to its antitumor effects.

Formula: C₉H₁₄N₂O₁₅P₃F

Purity: Min. 95%

Molecular weight: 502.13 g/mol

Ref: 3D-NF32079

5-Fluorouridine 5'-Triphosphate

CAS: 3828-96-4

Formula: C₉H₁₄FN₂O₁₅P₃

Color and Shape: Neat

Molecular weight: 502.132

Ref: TR-F532520

5-Fluoro-UTP trisodium

CAS: 3828-96-4

Please enquire for more information about 5-Fluoro-UTP trisodium including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₉H₁₄FN₂O₁₅P₃•Na₃

Purity: Min. 95%

Molecular weight: 571.1 g/mol

Ref: 3D-FF183495