CAS 38304-91-5
:Minoxidil
Description:
Minoxidil, with the CAS number 38304-91-5, is a potent vasodilator primarily used in the treatment of hypertension and as a topical solution for hair loss. It is a white to off-white crystalline powder that is soluble in water and alcohol, making it suitable for various formulations. Minoxidil acts by relaxing blood vessels, which helps to lower blood pressure, and it promotes hair regrowth by enhancing blood flow to hair follicles. The compound has a molecular formula of C9H15N5O and a relatively high molecular weight. Its mechanism of action involves the opening of potassium channels, leading to hyperpolarization of vascular smooth muscle cells. While generally well-tolerated, minoxidil can cause side effects such as fluid retention and increased heart rate. It is important to note that minoxidil is often used in conjunction with other antihypertensive agents to mitigate its side effects. In topical applications, it is commonly found in concentrations of 2% and 5%, with the latter being more effective for promoting hair growth.
Formula:C9H15N5O
InChI:InChI=1/C9H15N5O/c10-7-6-8(12-9(11)14(7)15)13-4-2-1-3-5-13/h6H,1-5,10H2,(H2,11,12)
InChI key:InChIKey=ZFMITUMMTDLWHR-UHFFFAOYSA-N
SMILES:NC1=CC(=NC(N)=N1=O)N2CCCCC2
Synonyms:- (2E)-6-amino-2-imino-4-(piperidin-1-yl)pyrimidin-1(2H)-ol
- 2,4-Diamino-6-(1-piperidinyl)-pyrimidine-3-oxide
- 2,4-Diamino-6-piperidino-pyrimidine-3-oxide
- 2,4-Diamino-6-piperidinopyrimidine 3-N-oxide
- 2,4-Diamino-6-piperidinopyrimidine 3-oxide
- 2,4-Pyrimidinediamine, 2,3-dihydro-6-(1-piperidinyl)-, 3-oxide
- 2,4-Pyrimidinediamine, 6-(1-piperidinyl)-, 3-oxide
- 2,6-Diamino-4-(piperidin-1-yl)pyrimidin-1-ium-1-olate
- 2,6-Diamino-4-(piperidin-1-yl)pyrimidine 1-oxide
- 6-(1-Piperidinyl)-2,4-pyrimidinediamine-3-oxide
- 6-(Piperidin-1-Yl)Pyrimidine-2,4-Diamine 3-Oxide
- 6-Amino-1,2-dihydro-1-hydroxy-2-imino-4-piperidinopyrimidine
- 6-Amino-1,2-dihydro-1-hydroxy-2-imino-4-piperodinopyrimidine
- Alopexil
- Alostil
- Loniten
- Lonolox
- Minoximen
- Mintop
- Normoxidil
- PDP
- Pierminox
- Prexidil
- RiUP
- Riup X5
- Rogaine
- Tricoxidil
- U 10858
- Minoxidil
- 2,4-diamino-6-piperidinopyrimidine3-n-oxide
- minossidile
- regain
- 4-pyrimidinediamine,6-(1-piperidinyl)-3-oxide
- 6-(1-PIPERIDINYL)PYRIMIDINE-2,4-DIAMINE 3-OXIDE
- 2,3-dihydro-3-hydroxy-2-imino-6-(1-piperidinyl)-4-pyrimidinamine
- 2,4-diamino-6-piperidino-pyrimidin3-oxide
- MONOXIDIL
- 2,4-diamino-6-piperidinilpirimidina-3-ossido
- See more synonyms
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