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CAS 38313-48-3

:

3′,5′-Anhydrothymidine

Description:
3′,5′-Anhydrothymidine is a nucleoside analog derived from thymidine, characterized by the absence of the 3′ and 5′ hydroxyl groups, which are replaced by anhydro linkages. This structural modification imparts unique properties to the compound, making it of interest in biochemical and pharmaceutical research. It is typically a white to off-white crystalline powder, soluble in water and organic solvents, which facilitates its use in various applications. The compound exhibits potential antiviral and anticancer activities, as it can interfere with nucleic acid synthesis. Its mechanism of action often involves incorporation into DNA, leading to chain termination during replication. Additionally, 3′,5′-Anhydrothymidine can serve as a valuable tool in studying nucleoside metabolism and the development of therapeutic agents targeting viral infections or cancer. Safety and handling precautions should be observed, as with any chemical substance, due to potential toxicity and reactivity.
Formula:C10H12N2O4
InChI:InChI=1/C10H12N2O4/c1-5-3-12(10(14)11-9(5)13)8-2-6-7(16-8)4-15-6/h3,6-8H,2,4H2,1H3,(H,11,13,14)/t6-,7+,8+/m0/s1
InChI key:InChIKey=OAWLMYIJZBBZTP-XLPZGREQSA-N
SMILES:O=C1N([C@H]2C[C@]3([C@](O2)(CO3)[H])[H])C=C(C)C(=O)N1
Synonyms:
  • 1-[(1S,3R,5R)-4,7-dioxabicyclo[3.2.0]heptan-3-yl]-5-methyl-pyrimidine-2,4-dione
  • 2,6-Dioxabicyclo[3.2.0]heptane, thymidine deriv.
  • 38313-48-3
  • 3′,5′-Anhydrothymidine
  • Thymidine, 3',5'-anhydro-
  • Thymidine, 3′,5′-anhydro-
  • 3',5'-Anhydrothymidine
  • 2,5'-Anhydro-thymidine
  • 3,5'-thymidine,anhydrous
  • Anhydrolhymidine
  • See more synonyms
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