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CAS 38315-43-4

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17-Phenyl-ω-trinor-PGE2

Description:
17-Phenyl-ω-trinor-PGE2, with the CAS number 38315-43-4, is a synthetic analog of prostaglandin E2 (PGE2), which is a bioactive lipid involved in various physiological processes, including inflammation and regulation of blood flow. This compound features a phenyl group and modifications to the prostaglandin structure that enhance its stability and alter its biological activity. Typically, such modifications can affect the compound's receptor affinity and efficacy, making it useful in research to study prostaglandin pathways and their implications in various biological systems. The presence of the phenyl group may also influence its solubility and interaction with biological membranes. As a synthetic derivative, 17-Phenyl-ω-trinor-PGE2 is often utilized in pharmacological studies to explore its potential therapeutic applications, particularly in the context of inflammation and pain management. However, specific characteristics such as solubility, melting point, and biological activity would require empirical data for precise evaluation.
Formula:C23H30O5
InChI:InChI=1S/C23H30O5/c24-18(13-12-17-8-4-3-5-9-17)14-15-20-19(21(25)16-22(20)26)10-6-1-2-7-11-23(27)28/h1,3-6,8-9,14-15,18-20,22,24,26H,2,7,10-13,16H2,(H,27,28)/b6-1-,15-14+/t18-,19+,20+,22+/m0/s1
InChI key:InChIKey=FOBVMYJQWZOGGJ-XYRJXBATSA-N
SMILES:C(/C=C\CCCC(O)=O)[C@@H]1[C@@H](/C=C/[C@H](CCC2=CC=CC=C2)O)[C@H](O)CC1=O
Synonyms:
  • 5-Heptenoic acid, 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]-5-oxocyclopentyl]-, (5Z)-
  • (5Z)-7-[(1R,2R,3R)-3-Hydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]-5-oxocyclopentyl]-5-heptenoic acid
  • 5-Heptenoic acid, 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-pentenyl]-5-oxocyclopentyl]-, (5Z)-
  • 5-Heptenoic acid, 7-[3-hydroxy-2-(3-hydroxy-5-phenyl-1-pentenyl)-5-oxocyclopentyl]-, [1R-[1α(Z),2β(1E,3S*),3α]]-
  • 17-Phenyl-18,19,20-trinorprostaglandin E2
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Found 2 products.
  • 17-Phenyl-trinor-prostaglandin E2

    Controlled Product
    CAS:
    Formula:C23H30O5
    Color and Shape:Neat
    Molecular weight:386.481

    Ref: TR-P337393

    25mg
    35,414.00€
  • 17-phenyl trinor Prostaglandin E2

    CAS:
    <p>17-Phenyl trinor Prostaglandin E2 (17-phenyl trinor PGE2) is a synthetic analog of PGE2, functioning as an agonist at the EP1 and EP3 receptors. It induces contraction of the guinea pig ileum at a 11 µM concentration and displays slightly less potency than PGE2 in stimulating the gerbil colon and rat uterus. Notably, with an ED50 value of 350 µg/kg, 17-phenyl trinor PGE2 exhibits 4.4 times greater antifertility efficacy in hamsters compared to PGE2.</p>
    Formula:C23H30O5
    Color and Shape:Solid
    Molecular weight:386.5