CAS 38339-06-9

Homovanillic acid sulfate

Description:

Homovanillic acid sulfate is a chemical compound that is a sulfate ester of homovanillic acid, which is a metabolite of dopamine. It is characterized by its aromatic structure, featuring a methoxy group and a carboxylic acid group, which contribute to its biological activity. The sulfate group enhances its solubility in water, facilitating its transport and metabolism in biological systems. Homovanillic acid sulfate is often studied in the context of neurochemistry, particularly in relation to dopamine metabolism and its implications in various neurological disorders. It is typically found in biological fluids and can serve as a biomarker for certain conditions. The compound is also of interest in pharmacological research due to its potential effects on neurotransmitter systems. As with many metabolites, its concentration can vary based on physiological and pathological states, making it a valuable compound for understanding metabolic pathways and their alterations in disease.

Formula: C₉H₁₀O₇S

InChI: InChI=1S/C9H10O7S/c1-15-8-4-6(5-9(10)11)2-3-7(8)16-17(12,13)14/h2-4H,5H2,1H3,(H,10,11)(H,12,13,14)

InChI key: InChIKey=IACOAKYXFIWAQN-UHFFFAOYSA-N

SMILES: O(S(=O)(=O)O)C1=C(OC)C=C(CC(O)=O)C=C1

Synonyms:

• Benzeneacetic acid, 3-methoxy-4-(sulfooxy)-
• 2-(3-Methoxy-4-(sulfooxy)phenyl)acetic acid
• 3-Methoxy-4-(sulfooxy)benzeneacetic acid
• Homovanillic acid sulfate

Homovanillic Acid Sulfate

CAS: 38339-06-9

Homovanillic acid sulfate, a reagent for oxidative enzymes, indicates brain dopamine levels and diagnoses neuroblastoma and pheochromocytoma.

Formula: C₉H₁₀O₇S

Purity: 98%

Color and Shape: Solid

Molecular weight: 262.24

Ref: TM-TN6685

Homovanillic Acid 4-Sulfate

CAS: 38339-06-9

Formula: C₉H₁₀O₇S

Molecular weight: 262.23

Ref: 4Z-V-048020

Homovanillic Acid Sulfate Sodium Salt

Controlled Product

CAS: 38339-06-9

Applications A metabolite of Dihydroxyphenylacetic Acid (DOPAC) by catechol O-methyltransferase.
References Kuo, G.Y., et al.: Drug Metab. Disp., 16, 793 (1988),

Formula: C₉H₁₀O₇S

Color and Shape: Neat

Molecular weight: 262.24

Ref: TR-H669505

Homovanillic Acid Sulfate Sodium Salt-d3

Controlled Product

CAS: 38339-06-9

Applications A labelled metabolite of Dihydroxyphenylacetic acid (DOPAC) by catechol O-methyltransferase.
References Kuo, G.Y., et al.: Drug Metab. Disp., 16, 793 (1988),

Formula: C₉H₅D₃Na₂O₇S

Color and Shape: Neat

Molecular weight: 309.22

Ref: TR-H669507

Homovanillic acid sulfate sodium salt

CAS: 38339-06-9

Homovanillic acid sulfate sodium salt (HVA) is a metabolite of dopamine that is used to diagnose or monitor diseases related to the central nervous system. The HVA concentration in urine can be determined by colorimetric assay, which has been shown to be useful for identifying patients with Parkinson's disease and other degenerative diseases. HVA is also found in blood plasma and cerebrospinal fluid, as well as in many other body tissues. HVA levels are increased during pregnancy, because it is an intermediate in the biosynthesis of estradiol from testosterone. In addition, concentrations of HVA increase with age, due to decreased clearance rates.

Formula: C₉H₈Na₂O₇S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 306.2 g/mol

Ref: 3D-FH23861