CAS 383432-38-0
:CP-724714
Description:
CP-724714 is a small molecule that acts as a selective inhibitor of the epidermal growth factor receptor (EGFR) and is primarily studied for its potential therapeutic applications in cancer treatment. It is characterized by its ability to interfere with the signaling pathways that promote tumor growth and proliferation, making it a candidate for targeted cancer therapies. The compound exhibits a specific binding affinity to the EGFR, which is often overexpressed in various malignancies. In terms of its chemical structure, CP-724714 features a unique arrangement of functional groups that contribute to its biological activity and selectivity. The substance has undergone various preclinical studies to evaluate its efficacy and safety profile, with a focus on its potential to overcome resistance to existing EGFR-targeted therapies. As with many investigational drugs, ongoing research aims to further elucidate its pharmacokinetics, optimal dosing regimens, and potential side effects in clinical settings.
Formula:C27H27N5O3
Synonyms:- 2-Methoxy-N-[3-[4-[[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]phenyl]amino]-6-quinazolinyl]-2-propen-1-yl]acetamide
- (E)-2-Methoxy-N-(3-(4-(3-methyl-4-(6-methylpyridin-3-yloxy)phenylamino)quinazolin-6-yl)allyl)a
- CP-724
- CP-724714(E)-2-methoxy-N-(3-(4-(3-methyl-4-(6-methylpyridin-3-yloxy)phenylamino)quinazolin-6-yl)allyl)acetamide
- CP-724714 (E-Double bond)
- 2-Methoxy-N-[(2E)-3-[4-[[3-Methyl-4-[(6-Methyl-3-pyridinyl)oxy]phenyl]aMino]-6-quinazolinyl]-2-prope
- CP 724714;CP724714;CP-724714 (E-DOUBLE BOND)
- CP724
- CP 724714 NEW
- CS-2306
- CP-724;714;CP724;714;CP 724714;CP 724;714;CP724714;CP-724714
- 2-Methoxy-N-[(2E)-3-[4-[[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]phenyl]amino]-6-quinazolinyl]-2-propen-1-yl]acetamide
- 714
- Acetamide, 2-methoxy-N-[(2E)-3-[4-[[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]phenyl]amino]-6-quinazolinyl]-2-propen-1-yl]-
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Found 7 products.
2-Methoxy-N-[(2E)-3-[4-[[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]phenyl]amino]-6-quinazolinyl]-2-propen-1-yl]acetamide
CAS:Formula:C27H27N5O3Purity:98%Color and Shape:SolidMolecular weight:469.53502-Methoxy-N-[(2E)-3-[4-[[3-Methyl-4-[(6-Methyl-3-Pyridyl)Oxy] Phenyl]Amino]-6-Quinazolinyl]-2-Propenyl-1-Yl]Acetamide
CAS:<p>2-Methoxy-N-[(2E)-3-[4-[[3-Methyl-4-[(6-Methyl-3-Pyridyl)Oxy] Phenyl]Amino]-6-Quinazolinyl]-2-Propenyl-1-Yl]Acetamide</p>Purity:98%Molecular weight:469.54g/molCP-724714
CAS:<p>CP-724714 (CP724714) is an effective and selective HER2/ErbB2 inhibitor (IC50: 10 nM), >640-fold selectivity against EGFR, Abl, InsR, PDGFR, IRG-1R, Src, VEGFR2</p>Formula:C27H27N5O3Purity:97.1% - 98.82%Color and Shape:SolidMolecular weight:469.54CP 724714
CAS:<p>Inhibitor of ErbB2 (IC50 = 3 nM) and EGFR kinase (IC50 = 6.4 nM) with anti-proliferative effects. It inhibits ErbB2 receptor autophosphorylation and induces G1 cell cycle block. The CP 724714 treatment induces reduction of downstream ErbB2 receptor tyrosine kinase signalling, tumor cell apoptosis, release of caspase 3 and regression of tumors in in vivo and in vitro models.</p>Formula:C27H27N5O3Purity:Min. 95%Color and Shape:SolidMolecular weight:469.54 g/mol
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