CAS 38344-08-0

Bimatoprost acid

Description:

Bimatoprost acid, with the CAS number 38344-08-0, is a synthetic prostaglandin analog primarily known for its role in ophthalmology, particularly in the treatment of glaucoma and ocular hypertension. It is a derivative of bimatoprost, which is used to enhance eyelash growth and is also effective in lowering intraocular pressure. The substance exhibits characteristics typical of prostaglandin analogs, including the ability to increase the outflow of aqueous humor from the eye, thereby reducing pressure. Bimatoprost acid is typically a white to off-white solid and is soluble in organic solvents. Its mechanism of action involves the activation of specific receptors in the eye, leading to physiological changes that facilitate fluid drainage. Additionally, it has been studied for its potential effects on hair follicles, contributing to its use in cosmetic applications. As with many pharmacological agents, safety and efficacy are paramount, and it is essential to consider potential side effects and contraindications when used therapeutically.

Formula: C₂₃H₃₂O₅

InChI: InChI=1S/C23H32O5/c24-18(13-12-17-8-4-3-5-9-17)14-15-20-19(21(25)16-22(20)26)10-6-1-2-7-11-23(27)28/h1,3-6,8-9,14-15,18-22,24-26H,2,7,10-13,16H2,(H,27,28)/b6-1-,15-14+/t18-,19+,20+,21-,22+/m0/s1

InChI key: InChIKey=YFHHIZGZVLHBQZ-KDACTHKWSA-N

SMILES: C(/C=C\CCCC(O)=O)[C@@H]1[C@@H](/C=C/[C@H](CCC2=CC=CC=C2)O)[C@H](O)C[C@@H]1O

Synonyms:

• U-35687
• 17-Phenyl-18,19,20-trinorprostaglandin F2α
• (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-5-heptenoic acid
• 17-Phenyl-18,19,20-trinorprostaglandin F2α
• 5-Heptenoic acid, 7-[3,5-dihydroxy-2-(3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl]-, [1R-[1α(Z),2β(1E,3S*),3α,5α]]-
• Bimatoprost acid
• (5Z,13E,15S)-9α,11α,15-Trihydroxy-17-phenyl-18,19,20-trinorprosta-5,13-diene-1-oic acid
• 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-, (5Z)-
• 17-Phenyltrinorprostagrandin F2α
• (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxy-17-phenyl-18,19,20-trinorprosta-5,13-diene-1-oic acid
• 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-pentenyl]cyclopentyl]-, (5Z)-

(5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(S,E)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]hept-5-enoic acid

CAS: 38344-08-0

Formula: C₂₃H₃₂O₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 388.4972

Ref: IN-DA0038SE

Bimatoprost Acid

CAS: 38344-08-0

Formula: C₂₃H₃₂O₅

Color and Shape: Off-White Solid

Molecular weight: 388.50

Ref: 4Z-B-247

Bimatoprost acid

CAS: 38344-08-0

Bimatoprost acid

Purity: ≥95%

Molecular weight: 388.5g/mol

Ref: 54-BUP02540

Bimatoprost Acid

CAS: 38344-08-0

Color and Shape: Neat

Ref: 86-MM3603.02

Bimatoprost acid

CAS: 38344-08-0

Bimatoprost acid (17-phenyl trinor PGF2α) is a metabolically stable analog of PGF2α and has a potential antagonistic activity for the FP receptor.

Formula: C₂₃H₃₂O₅

Purity: 99.29%

Color and Shape: Solid

Molecular weight: 388.5

Ref: TM-T20939

Bimatoprost Acid

Controlled Product

CAS: 38344-08-0

Applications Bimatoprost Acid is an impurity of the antiglaucoma agent Bimatoprost (B386820).Bimatoprost Acid is a metabolically stable analog of PGF2α (P838625) and is a potent agonist for the FP receptor.
References Balapure, A.K. et al.: Biochem. Pharmacol., 38, 2375 (1989); Hellberg, M.R. et al.: J. Ocular Pharmacol. Ther., 19, 97 (2003); Krishna, P.M. et al.: J. Pharm. res., 4, 2381 (2011);

Formula: C₂₃H₃₂O₅

Color and Shape: White To Off-White

Molecular weight: 388.50

Ref: TR-B386820

Bimatoprost Acid

CAS: 38344-08-0

Formula: C₂₃H₃₂O₅

Molecular weight: 388.50

Ref: ST-EA-CP-B40001

Bimatoprost acid

CAS: 38344-08-0

FP receptor ligand; activator of PGF2αR

Formula: C₂₃H₃₂O₅

Purity: Min. 95 Area-%

Color and Shape: Clear Liquid

Molecular weight: 388.5 g/mol

Ref: 3D-BB173258