CAS 38353-06-9

5-Bromo-2(1H)-pyrimidinone

Description:

5-Bromo-2(1H)-pyrimidinone is a heterocyclic organic compound characterized by its pyrimidine ring structure, which includes a bromine substituent at the 5-position and a carbonyl group at the 2-position. This compound is typically a white to off-white solid and is soluble in polar organic solvents. It exhibits properties typical of pyrimidinones, such as the ability to participate in hydrogen bonding due to the presence of the carbonyl and nitrogen atoms in the ring. The bromine atom introduces a halogen functionality, which can enhance reactivity in various chemical reactions, including nucleophilic substitutions and coupling reactions. 5-Bromo-2(1H)-pyrimidinone is of interest in medicinal chemistry and pharmaceutical research, often serving as a building block for the synthesis of biologically active compounds. Its molecular structure allows for potential interactions with biological targets, making it a candidate for further investigation in drug development. Safety data should be consulted for handling and usage, as with any chemical substance.

Formula: C₄H₃BrN₂O

InChI: InChI=1S/C4H3BrN2O/c5-3-1-6-4(8)7-2-3/h1-2H,(H,6,7,8)

InChI key: InChIKey=VTUDATOSQGYWML-UHFFFAOYSA-N

SMILES: BrC1=CNC(=O)N=C1

Synonyms:

• 2(1H)-Pyrimidinone, 5-bromo-
• 2-Hydroxy-5-Bromopyrimidine
• 2-Oxo-5-bromopyrimidine
• 2-Pyrimidinol, 5-bromo-
• 5-Bromo-1H-pyrimidin-2-one
• 5-Bromo-2(1H)-pyrimidinone
• 5-Bromo-2(1h)-pyrimidinon
• 5-Bromo-2-Hydroxyprimidine
• 5-Bromo-2-Pyrimidinone
• 5-Bromo-2-hydroxypyridmidine
• 5-Bromopyrimidin-2(1H)-One
• 5-Bromopyrimidin-2-ol
• NSC 528730

5-Bromo-2-hydroxypyrimidine

CAS: 38353-06-9

Formula: C₄H₃BrN₂O

Purity: >95.0%(GC)

Color and Shape: Light orange to Yellow to Green powder to crystal

Molecular weight: 174.99

Ref: 3B-B2848

5-Bromo-2-hydroxypyrimidine

CAS: 38353-06-9

Formula: C₄H₃BrN₂O

Purity: 96%

Color and Shape: Solid

Molecular weight: 174.9834

Ref: IN-DA003MHC

5-Bromo-2-hydroxypyrimidine

CAS: 38353-06-9

Formula: C₄H₃BrN₂O

Molecular weight: 174.99

Ref: 7W-GK6426

5-Bromo-1,2-dihydro-2-oxopyrimidine

CAS: 38353-06-9

5-Bromo-1,2-dihydro-2-oxopyrimidine

Formula: C₄H₃BrN₂O

Purity: 98%

Color and Shape: pale yellow solid

Molecular weight: 174.98g/mol

Ref: 54-OR8599

Macitentan Impurity 32

CAS: 38353-06-9

Formula: C₄H₃BrN₂O

Molecular weight: 174.99

Ref: 4Z-M-128037

5-Bromo-2-hydroxypyrimidine

Controlled Product

CAS: 38353-06-9

Applications 5-Bromo-2-hydroxypyrimidine (cas# 38353-06-9) is a compound useful in organic synthesis.

Formula: C₄H₃BrN₂O

Color and Shape: Neat

Molecular weight: 174.98

Ref: TR-B684475

5-Bromo-2-hydroxypyrimidine

CAS: 38353-06-9

Formula: C₄H₃BrN₂O

Purity: 96%

Color and Shape: Solid

Molecular weight: 174.985

Ref: 10-F036375

5-Bromo-2-hydroxypyrimidine

CAS: 38353-06-9

5-Bromo-2-hydroxypyrimidine is a potent inhibitor of aldehyde oxidase, an enzyme that is involved in the production of reactive oxygen species. This drug has been shown to inhibit the growth of human liver cancer cells in vivo and exhibits cytotoxic effects on human leukemia cells. 5-Bromo-2-hydroxypyrimidine inhibits the activity of aldehyde oxidase by forming tautomers with a variety of different functional groups, including hydration, acid solutions, and inhibition activity. The tautomeric properties of 5-bromo-2-hydroxypyrimidine make it an effective inhibitor of aldehyde oxidase due to its ability to bind to various sites on the enzyme.

Formula: C₄H₃BrN₂O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 174.98 g/mol

Ref: 3D-FB01959