CAS 38353-09-2

2(1H)-Pyrimidinone, hydrochloride (1:1)

Description:

2(1H)-Pyrimidinone, hydrochloride (1:1), with the CAS number 38353-09-2, is a chemical compound characterized by its pyrimidinone structure, which features a six-membered aromatic ring containing nitrogen atoms. This compound typically appears as a white to off-white crystalline solid and is soluble in water due to the presence of the hydrochloride salt form, which enhances its solubility and stability. The presence of the pyrimidinone moiety suggests potential biological activity, as pyrimidine derivatives are often involved in various biochemical processes and can serve as precursors for nucleic acids. The hydrochloride form indicates that it is a salt, which can influence its pharmacological properties, such as absorption and bioavailability. In laboratory settings, it may be utilized in organic synthesis, medicinal chemistry, or as a reagent in various chemical reactions. Safety data should be consulted for handling and storage, as with any chemical substance, to ensure proper precautions are taken.

Formula: C₄H₄N₂O·ClH

InChI: InChI=1S/C4H4N2O.ClH/c7-4-5-2-1-3-6-4;/h1-3H,(H,5,6,7);1H

InChI key: InChIKey=IAJINJSFYTZPEJ-UHFFFAOYSA-N

SMILES: O=C1NC=CC=N1.Cl

Synonyms:

• 1,2-Dihydropyrimidin-2-one hydrochloride
• 2(1H)-Pyrimidinone hydrochloride
• 2(1H)-Pyrimidinone, hydrochloride (1:1)
• 2(1H)-Pyrimidinone, monohydrochloride
• 2-Hydroxypyrimidine monohydrochloride
• 2-Hydroxypyrimidine, HCl
• 2-Pyrimidinol hydrochloride
• 2-Pyrimidinone hydrochloride
• Pyrimidin-2-one monohydrochloride
• Pyrimidine-2-Ol Hydrochloride
• pyrimidin-2(1H)-one
• pyrimidin-2(1H)-one hydrochloride (1:1)

Pyrimidin-2-ol hydrochloride

CAS: 38353-09-2

Formula: C₄H₅ClN₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 132.5483

Ref: IN-DA003HG3

2-Hydroxypyrimidine hydrochloride

CAS: 38353-09-2

2-Hydroxypyrimidine hydrochloride

Formula: C₄H₄N₂O·ClH

Purity: ≥95%

Color and Shape: yellow crystalline powder

Molecular weight: 132.55g/mol

Ref: 54-OR61010

2-Hydroxypyrimidine hydrochloride

CAS: 38353-09-2

Formula: C₄H₄N₂OHCl

Molecular weight: 132.55

Ref: 7W-GK5223

2-Hydroxypyrimidine Hydrochloride

CAS: 38353-09-2

Formula: C₄H₄N₂O·HCl

Purity: >98.0%(T)(HPLC)

Color and Shape: Light yellow to Yellow to Orange powder to crystal

Molecular weight: 132.55

Ref: 3B-H0480

2-Hydroxypyrimidine hydrochloride

CAS: 38353-09-2

Formula: C₄H₅ClN₂O

Purity: 97%

Color and Shape: Solid

Molecular weight: 132.55

Ref: 10-F147200

2-Hydroxypyrimidine Hydrochloride

Controlled Product

CAS: 38353-09-2

Applications 2-Hydroxypyrimidine Hydrochloride, is used as a reagent in the synthesis of BI 207524, an indole diamide NS5B thumb pocket 1 inhibitor with improved potency for potential treatment of chronic hepatitis C virus infection.
References Beaulieu, P.L., et al.: J. Med. Chem., 57, 10130 (2014)

Formula: C₄H₄N₂O·HCl

Color and Shape: Neat

Molecular weight: 132.55

Ref: TR-H953040

2-Hydroxypyrimidine HCl

CAS: 38353-09-2

2-Hydroxypyrimidine HCl is a compound that is soluble in water and has an appearance of white crystals. It can be used as a metal ion chelator, as well as an inhibitor of aldehyde oxidase. 2-Hydroxypyrimidine HCl has been shown to be effective in the treatment of solid tumours and may also be used for the treatment of neoplastic diseases such as leukemia. The compound is cytotoxic and inhibits DNA synthesis, which may lead to cell death. 2-Hydroxypyrimidine HCl also has functional groups that are responsible for its ability to inhibit aldehyde oxidase and 5-aminouracil (5AU).

Formula: C₄H₅ClN₂O

Purity: Min. 95%

Color and Shape: White To Yellow Solid

Molecular weight: 132.55 g/mol

Ref: 3D-FH30092