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CAS 38363-40-5

:

Penbutolol

Description:
Penbutolol is a non-selective beta-adrenergic antagonist, primarily used in the treatment of hypertension and certain types of heart conditions. It is characterized by its ability to block beta-1 and beta-2 adrenergic receptors, which helps to reduce heart rate and lower blood pressure. The chemical structure of penbutolol includes a butanol side chain, contributing to its pharmacological properties. It is typically administered orally and has a moderate bioavailability. Penbutolol is known for its relatively long half-life, allowing for once-daily dosing in clinical practice. Additionally, it may exhibit intrinsic sympathomimetic activity, which means it can partially stimulate beta receptors while blocking them, potentially leading to fewer side effects compared to other beta-blockers. Common side effects may include fatigue, dizziness, and gastrointestinal disturbances. As with any medication, it is essential to monitor patients for adverse reactions and interactions with other drugs. Overall, penbutolol serves as an effective option in managing cardiovascular conditions, particularly in patients who may benefit from a non-selective beta-blocker.
Formula:C18H29NO2
InChI:InChI=1S/C18H29NO2/c1-18(2,3)19-12-15(20)13-21-17-11-7-6-10-16(17)14-8-4-5-9-14/h6-7,10-11,14-15,19-20H,4-5,8-9,12-13H2,1-3H3/t15-/m0/s1
InChI key:InChIKey=KQXKVJAGOJTNJS-HNNXBMFYSA-N
SMILES:O(C[C@H](CNC(C)(C)C)O)C1=C(C=CC=C1)C2CCCC2
Synonyms:
  • (-)-Isopenbutolol
  • (2S)-1-(2-Cyclopentylphenoxy)-3-[(1,1-dimethylethyl)amino]-2-propanol
  • 1-(Tert-Butylamino)-3-(2-Cyclopentylphenoxy)Propan-2-Ol
  • 2-Propanol 1-(2-cyclopentylphenoxy)-3-[(1,1-dimethylethyl)amino]-, (2S)-
  • 2-Propanol, 1-(2-cyclopentylphenoxy)-3-((1,1-dimethylethyl)amino)-, (S)-
  • Betapressin
  • Brn 4484348
  • Ccris 2855
  • Hoe 893
  • Hoe 893D
  • See more synonyms
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Found 3 products.