CAS 3847-29-8

Erythromycin lactobionate

Description:

Erythromycin lactobionate is a macrolide antibiotic derived from the bacterium Saccharopolyspora erythraea. It is primarily used to treat various bacterial infections, particularly those caused by Gram-positive bacteria and some Gram-negative organisms. The substance is characterized by its lactobionate salt form, which enhances its solubility in water, making it suitable for intravenous administration. Erythromycin lactobionate exhibits a broad spectrum of activity against respiratory tract infections, skin infections, and certain sexually transmitted diseases. Its mechanism of action involves inhibiting bacterial protein synthesis by binding to the 50S ribosomal subunit, thereby preventing the growth and reproduction of bacteria. The compound is generally well-tolerated, though it may cause gastrointestinal side effects and has potential interactions with other medications due to its effect on liver enzymes. As with all antibiotics, appropriate use is crucial to prevent the development of antibiotic resistance.

Formula: C₃₇H₆₇NO₁₃·C₁₂H₂₂O₁₂

InChI: InChI=1S/C37H67NO13.C12H22O12/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26;13-1-3(15)10(7(18)8(19)11(21)22)24-12-9(20)6(17)5(16)4(2-14)23-12/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3;3-10,12-20H,1-2H2,(H,21,22)/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-;3-,4-,5+,6+,7-,8-,9-,10-,12+/m11/s1

InChI key: InChIKey=NNRXCKZMQLFUPL-WBMZRJHASA-N

SMILES: O([C@@H]1[C@@H](C)[C@H](O[C@H]2C[C@](OC)(C)[C@@H](O)[C@H](C)O2)[C@@H](C)C(=O)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@]1(C)O)[C@H]3[C@H](O)[C@@H](N(C)C)C[C@@H](C)O3.[C@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)([C@@H]([C@H](C(O)=O)O)O)[C@@H](CO)O

Synonyms:

• (2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}hexanoic acid - (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione (1:1) (non-preferred name)
• 4-O-beta-D-Galactopyranosyl-D-gluconic acid compd. with erythromycin
• <span class="text-smallcaps">D</smallcap>-Gluconic acid, 4-O-β-<smallcap>D</span>-galactopyranosyl-, compd. with erythromycin (1:1)
• D-Gluconic acid, 4-O-beta-D-galactopyranosyl-, compd. with erythromycin (1:1) (9CI)
• Erythrocin Lactobionate IV
• Erythrocin lactobionate
• Erythromycin lactobionate (1:1) (salt)
• Erythromycin mono(4-O-beta-D-galactopyranosyl-D-gluconate) (salt)
• Erythromycin, 4-O-beta-D-galactopyranosyl-D-gluconate (salt)
• Erythromycin, 4-O-β-<span class="text-smallcaps">D</smallcap>-galactopyranosyl-<smallcap>D</span>-gluconate (1:1)
• Erythromycin, 4-O-β-<span class="text-smallcaps">D</smallcap>-galactopyranosyl-<smallcap>D</span>-gluconate (salt)
• Erythromycin. compd. with lactobionic acid
• Lactobionic acid, compd. with erythromycin (1:1)
• Oxacyclotetradecane, erythromycin deriv.
• Erythromycin, 4-O-β-D-galactopyranosyl-D-gluconate (1:1)

ERYTHROMYCIN LACTOBIONATE CRS

CAS: 3847-29-8

ERYTHROMYCIN LACTOBIONATE CRS

Formula: C₄₉H₈₉NO₂₅

Molecular weight: 1092.223

Ref: 41-Y0001848

Erythromycin Lactobionate

CAS: 3847-29-8

Erythromycin and its derivatives; salts thereof

Formula: C₃₇H₆₇NO₁₃·C₁₂H₂₂O₁₂

Color and Shape: White Off-White Powder

Molecular weight: 1091.57237

Ref: 45-1247003

Erythromycin Lactobionate

CAS: 3847-29-8

Formula: C₄₉H₈₉NO₂₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 1092.2227

Ref: IN-DA0079PQ

Erythromycin lactobionate

CAS: 3847-29-8

Erythromycin, a macrolide antibiotic, inhibits bacterial protein synthesis, effective against Streptococcus and Staphylococcus, and affects CYP3A4 metabolism.

Formula: C₄₉H₈₉NO₂₅

Color and Shape: Solid

Molecular weight: 1092.233

Ref: TM-T37433

Erythromycin Lactobionate

Controlled Product

CAS: 3847-29-8

Applications Erythromycin Lactobionate is an antibiotic used to reduce the prevalence of drug resistant bacteria as well as keeping constant the efficacy of other antibacterial drugs.
References Kiso, S. et al.: Anticanc. Res., 20, 2827 (2000); Broad, J. et al.: Brit. J. Pharm., 168,1859 (2013); Itoh, Z., et al.: Antimicrob. Agents Chemother., 26, 863(1984)

Formula: C₃₇H₆₇NO₁₃·C₁₂H₂₂O₁₂

Color and Shape: Neat

Molecular weight: 1092.22

Ref: TR-E650040

Erythromycin iactobionate

CAS: 3847-29-8

Erythromycin lactobionate is a macrolide antibiotic, which is derived from the bacterium *Saccharopolyspora erythraea*. Its mode of action involves binding to the 50S subunit of the bacterial ribosome, thereby inhibiting protein synthesis and leading to the suppression of bacterial growth. This mechanism effectively targets gram-positive bacteria and some gram-negative bacteria, making it a crucial agent in the fight against various bacterial infections.

Formula: C₄₉H₈₇NO₂₄

Purity: Min. 95%

Color and Shape: White To Off-White Solid

Molecular weight: 1,074.21 g/mol

Ref: 3D-AE37145

Erythromycin lactobioate A

CAS: 3847-29-8

Formula: C₃₇H₆₇NO₁₃C₁₂H₂₂O₁₂

Molecular weight: 733.94 : 358.3

Ref: ST-EA-CP-E18027