CAS 3847-29-8: Erythromycin lactobionate
Description:Erythromycin lactobionate is a macrolide antibiotic derived from the bacterium Saccharopolyspora erythraea. It is primarily used to treat various bacterial infections, particularly those caused by Gram-positive bacteria and some Gram-negative organisms. The substance is characterized by its lactobionate salt form, which enhances its solubility in water, making it suitable for intravenous administration. Erythromycin lactobionate exhibits a broad spectrum of activity against respiratory tract infections, skin infections, and certain sexually transmitted diseases. Its mechanism of action involves inhibiting bacterial protein synthesis by binding to the 50S ribosomal subunit, thereby preventing the growth and reproduction of bacteria. The compound is generally well-tolerated, though it may cause gastrointestinal side effects and has potential interactions with other medications due to its effect on liver enzymes. As with all antibiotics, appropriate use is crucial to prevent the development of antibiotic resistance.
Formula:C37H67NO13·C12H22O12
InChI:InChI=1S/C37H67NO13.C12H22O12/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26;13-1-3(15)10(7(18)8(19)11(21)22)24-12-9(20)6(17)5(16)4(2-14)23-12/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3;3-10,12-20H,1-2H2,(H,21,22)/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-;3-,4-,5+,6+,7-,8-,9-,10-,12+/m11/s1
InChI key:InChIKey=NNRXCKZMQLFUPL-WBMZRJHASA-N
SMILES:O=C(O)C(O)C(O)C(OC1OC(CO)C(O)C(O)C1O)C(O)CO.O=C1OC(CC)C(O)(C)C(O)C(C(=O)C(C)CC(O)(C)C(OC2OC(C)CC(N(C)C)C2O)C(C)C(OC3OC(C)C(O)C(OC)(C)C3)C1C)C
- Synonyms:
- (2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}hexanoic acid - (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione (1:1) (non-preferred name)
- 4-O-beta-D-Galactopyranosyl-D-gluconic acid compd. with erythromycin
- <span class="text-smallcaps">D</smallcap>-Gluconic acid, 4-O-β-<smallcap>D</span>-galactopyranosyl-, compd. with erythromycin (1:1)
- D-Gluconic acid, 4-O-beta-D-galactopyranosyl-, compd. with erythromycin (1:1) (9CI)
- Erythrocin Lactobionate IV
- Erythrocin lactobionate
- Erythromycin lactobionate (1:1) (salt)
- Erythromycin mono(4-O-beta-D-galactopyranosyl-D-gluconate) (salt)
- Erythromycin, 4-O-beta-D-galactopyranosyl-D-gluconate (salt)
- Erythromycin, 4-O-β-<span class="text-smallcaps">D</smallcap>-galactopyranosyl-<smallcap>D</span>-gluconate (1:1)
- See more synonyms
- Erythromycin, 4-O-β-<span class="text-smallcaps">D</smallcap>-galactopyranosyl-<smallcap>D</span>-gluconate (salt)
- Erythromycin. compd. with lactobionic acid
- Lactobionic acid, compd. with erythromycin (1:1)
- Oxacyclotetradecane, erythromycin deriv.
- Erythromycin, 4-O-β-D-galactopyranosyl-D-gluconate (1:1)
- Erythromycin, 4-O-β-D-galactopyranosyl-D-gluconate (salt)
