CAS 38520-57-9

N-Acetylcysteine amide

Description:

N-Acetylcysteine amide (NAC amide) is a derivative of the amino acid cysteine, characterized by the presence of an acetyl group attached to the nitrogen atom of the cysteine side chain. This compound is known for its antioxidant properties, which are attributed to its ability to replenish intracellular levels of glutathione, a critical antioxidant in the body. NAC amide is often studied for its potential therapeutic applications, including its role in protecting against oxidative stress and inflammation. It is soluble in water and exhibits stability under various pH conditions, making it suitable for various formulations. Additionally, NAC amide is considered to have a lower odor compared to its parent compound, N-acetylcysteine, which can enhance its acceptability in certain applications. Research into its pharmacological effects suggests potential benefits in respiratory health, liver protection, and neuroprotection, although further studies are needed to fully elucidate its mechanisms and efficacy in clinical settings.

Formula: C₅H₁₀N₂O₂S

InChI: InChI=1S/C5H10N2O2S/c1-3(8)7-4(2-10)5(6)9/h4,10H,2H2,1H3,(H2,6,9)(H,7,8)/t4-/m0/s1

InChI key: InChIKey=UJCHIZDEQZMODR-BYPYZUCNSA-N

SMILES: [C@@H](NC(C)=O)(C(N)=O)CS

Synonyms:

• (2R)-2-(Acetylamino)-3-mercaptopropanamide
• (2R)-2-Acetamido-3-sulfanylpropanamide
• (R)-2-Acetamido-3-mercaptopropanamide
• N-Acetyl-<span class="text-smallcaps">L</span>-cysteinamide
• N-Acetyl-L-cysteinamide
• N-Acetylcysteine amide
• Propanamide,2-(acetylamino)-3-mercapto-, (R)-
• Propanamide, 2-(acetylamino)-3-mercapto-, (2R)-

(R)-2-Acetamido-3-mercaptopropanamide

CAS: 38520-57-9

Formula: C₅H₁₀N₂O₂S

Purity: 97%

Color and Shape: Solid

Molecular weight: 162.2101

Ref: IN-DA00368B

(R)-2-Acetamido-3-Mercaptopropanamide

CAS: 38520-57-9

(R)-2-Acetamido-3-Mercaptopropanamide

Purity: 96%

Molecular weight: 162.21g/mol

Ref: 54-OR1025331

N-acetylcysteine amide

CAS: 38520-57-9

N-acetylcysteine amide

Purity: ≥98%

Molecular weight: 162.21g/mol

Ref: 54-BUP13064

N-Acetylcysteine amide

CAS: 38520-57-9

Formula: C₅H₁₀N₂O₂S

Purity: ≥ 96%

Color and Shape: White to off-white solid

Molecular weight: 162.21

Ref: 7W-GL3691

Ac-Cys-NH2

CAS: 38520-57-9

Formula: C₅H₁₀N₂O₂S

Purity: >95.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 162.21

Ref: 3B-A3522

N-Acetylcysteine Amide

CAS: 38520-57-9

Formula: C₅H₁₀N₂O₂S

Molecular weight: 162.21

Ref: 4Z-A-336035

N-acetylcysteine amide

CAS: 38520-57-9

N-Acetylcysteine amide is a thiol antioxidant and a neuroprotective agent with cell permeability and blood-brain barrier permeability. Cost-effective and quality-assured.

Formula: C₅H₁₀N₂O₂S

Purity: 99.36% - ≥98%

Color and Shape: Solid

Molecular weight: 162.21

Ref: TM-T5518

N-Acetylcysteine Amide

CAS: 38520-57-9

Applications N-Acetylcysteine Amide is used for the treatment of acquired immune deficiency syndrome and HIV infection, an antidote for an acetaminophen toxicity. Also used as authentic imaging probe for accurate tracing of cells viability from beginning to end to distinguish apoptotic and necrotic cells, A thiol-based antioxidant and a precursor of glutathione (GSH), alleviates MTX-induced platelets apoptosis and oxidative damage.
References (1) Paul, M., et al.: PLoS One, 10, e0127558/1 (2015) (2) Ferreira, L. F., et al.: Med. Sci. Sports Exerc 43, 1025 (2011) (3) Khayyat, A., et al.: Toxicol. Lett. 241, 133 (2016)

Formula: C₅H₁₀N₂O₂S

Color and Shape: White To Off-White

Molecular weight: 162.21

Ref: TR-A172195

N-Acetylcysteine amide

CAS: 38520-57-9

N-Acetylcysteine amide (NACA) is a glutathione precursor that is used to prevent or treat oxidative stress. It has been shown to protect cells from death due to oxidative damage and radiation, as well as improve the quality of life in patients with eye disorders. NACA has also been shown to protect against neuronal death by inhibiting the activity of the enzyme that causes this type of cell death, nitric oxide synthase. NACA is an amide derivative of N-acetylcysteine that is synthesized by reacting cysteamine hydrochloride with acetic acid. The synthesis process involves the use of a coupling agent and a catalyst.

Formula: C₅H₁₀N₂O₂S

Purity: (¹H-Nmr) Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 162.21 g/mol

Ref: 3D-NBA52057

(R)-2-ACETAMIDO-3-MERCAPTOPROPANAMIDE

CAS: 38520-57-9

Purity: 98%

Molecular weight: 162.2100067

Ref: 10-F826996

N-Acetylcysteine Amide

CAS: 38520-57-9

Formula: C₅H₁₀N₂O₂S

Molecular weight: 162.21

Ref: 4Z-C-77105