CAS 38521-46-9

2-Mercaptonicotinic acid

Description:

2-Mercaptonicotinic acid, with the CAS number 38521-46-9, is an organic compound that features both a thiol (-SH) and a carboxylic acid (-COOH) functional group, making it a member of the mercapto acid family. It is a derivative of nicotinic acid, where a mercapto group is substituted at the 2-position of the pyridine ring. This compound is typically characterized by its ability to form chelates with metal ions due to the presence of the thiol group, which can enhance its utility in various applications, including coordination chemistry and biochemistry. 2-Mercaptonicotinic acid is often studied for its potential biological activities, including antioxidant properties and its role in metal ion transport. It is generally soluble in polar solvents, and its reactivity can be influenced by the pH of the environment, affecting its ionization state. Safety data should be consulted for handling, as thiol compounds can be toxic and have strong odors.

Formula: C₆H₅NO₂S

InChI: InChI=1S/C6H5NO2S/c8-6(9)4-2-1-3-7-5(4)10/h1-3H,(H,7,10)(H,8,9)

InChI key: InChIKey=WYKHFQKONWMWQM-UHFFFAOYSA-N

SMILES: C(O)(=O)C=1C(=S)NC=CC1

Synonyms:

• (2-thioxopyridin-3(2H)-ylidene)methanediolate
• 1,2-Dihydro-2-thioxo-3-pyridinecarboxylic acid
• 2-Mercapto-3-Pyridinecarboxylic Acid
• 2-Mercapto-3-carboxypyridine
• 2-Mercaptopyridine-3-Carboxylic Acid
• 2-Sulfanylidene-1H-pyridine-3-carboxylic acid
• 2-Sulfanylnicotinic Acid
• 2-Sulfanylpyridine-3-Carboxylic Acid
• 2-Thionicotinic Acid
• 2-Thioxo-1,2-Dihydropyridine-3-Carboxylate
• 2-Thioxo-1,2-dihydro-pyridine-3-carboxylic acid
• 3-Aza-2-thiosalicylic acid
• 3-Pyridinecarboxylic acid, 1,2-dihydro-2-thioxo-
• Labotest-Bb Lt01596005

2-Mercaptonicotinic Acid

CAS: 38521-46-9

Formula: C₆H₅NO₂S

Purity: >98.0%(T)(HPLC)

Color and Shape: Light yellow to Yellow to Green powder to crystaline

Molecular weight: 155.17

Ref: 3B-M1213

2-Mercaptonicotinic acid

CAS: 38521-46-9

Formula: C₆H₅NO₂S

Purity: 97%

Color and Shape: Solid

Molecular weight: 155.1744

Ref: IN-DA003HID

2-Thionicotinic acid

CAS: 38521-46-9

2-Thionicotinic acid

Formula: C₆H₅NO₂S

Purity: 97%

Color and Shape: yellow solid

Molecular weight: 155.1744g/mol

Ref: 54-OR28620

2-Thionicotinic Acid

CAS: 38521-46-9

Formula: C₆H₅NO₂S

Purity: 97%

Color and Shape: Solid, Light yellow powder

Molecular weight: 155.17

Ref: 10-F066075

2-Mercaptonicotinic acid

CAS: 38521-46-9

2-Mercaptonicotinic acid (2MNA) is an inhibitor of the P-glycoprotein, which is a multidrug resistance-associated protein. It prevents the transport of drugs and other molecules across the cell membrane. 2MNA has been shown to inhibit cancer cells in cervical cancer studies, and has been proven to reduce the toxicity of chemotherapy drugs in rats. 2MNA binds to p-glycoprotein and inhibits its function by forming a disulfide bond with cysteine residues on the transporter. 2MNA also has toxic effects on human serum and may be hazardous for use as a therapeutic agent.

Formula: C₆H₅NO₂S

Purity: Min. 95%

Molecular weight: 155.18 g/mol

Ref: 3D-FM00951