CAS 38524-82-2

Trifenofos

Description:

Trifenofos is an organophosphorus compound primarily used as an insecticide and acaricide in agricultural applications. It is characterized by its ability to inhibit acetylcholinesterase, an enzyme crucial for the proper functioning of the nervous system in insects, leading to paralysis and death. The substance is typically a colorless to pale yellow liquid with a faint odor, and it is relatively stable under normal conditions. Trifenofos is lipophilic, allowing it to penetrate biological membranes effectively. Its solubility in organic solvents is higher than in water, which influences its application methods and environmental behavior. While effective against a range of pests, trifenofos poses potential risks to non-target organisms, including humans, due to its toxicity. Therefore, its use is regulated in many countries, and safety precautions are essential during handling and application to minimize exposure and environmental impact. Proper management practices are crucial to mitigate any adverse effects associated with its use in agricultural settings.

Formula: C₁₁H₁₄Cl₃O₃PS

InChI: InChI=1S/C11H14Cl3O3PS/c1-3-5-19-18(15,16-4-2)17-11-9(13)6-8(12)7-10(11)14/h6-7H,3-5H2,1-2H3

InChI key: InChIKey=JJSBMWMYKICVIZ-UHFFFAOYSA-N

SMILES: O(P(SCCC)(OCC)=O)C1=C(Cl)C=C(Cl)C=C1Cl

Synonyms:

• 38524-82-2
• O-Ethyl S-propyl O-2,4,6-trichlorophenyl phosphorothiolate
• O-Ethyl-S-propyl-O-(2,4,6-trichlorphenyl)thiophosphat
• Phosphorothioic acid, O-ethyl S-propyl O-(2,4,6-trichlorophenyl) ester (9CI)
• Rh 218
• Thiophosphate de O-éthyle et de S-propyle et de O-(2,4,6-trichlorophényle)
• Trifenofos
• phosphorothioic acid, O-ethyl S-propyl O-(2,4,6-trichlorophenyl) ester

Trifenofos

CAS: 38524-82-2

Trifenofos is a potent protein kinase inhibitor that has shown promising anticancer activity in preclinical studies. It targets specific kinases involved in tumor growth and survival, leading to apoptosis or programmed cell death of cancer cells. Trifenofos is an analog of a natural toxin found in Chinese urine, which has been used for centuries in traditional medicine to treat various ailments. In addition to its anticancer properties, trifenofos also shows potential as an inhibitor of other diseases involving abnormal protein kinase activity. Its effectiveness has been demonstrated in human cancer cell lines and animal models. With its ability to selectively target cancer cells, trifenofos holds great promise as a potential therapeutic agent for the treatment of various cancers.

Formula: C₁₁H₁₄Cl₃O₃PS

Purity: Min. 95%

Molecular weight: 363.6 g/mol

Ref: 3D-NBA52482