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CAS 3861-76-5

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Clonitazene

Description:
Clonitazene is a synthetic compound classified as a benzodiazepine derivative, primarily known for its potent analgesic and sedative properties. It is characterized by its chemical structure, which includes a benzene ring fused to a diazepine ring, along with various substituents that enhance its pharmacological effects. Clonitazene exhibits a high affinity for the central nervous system, leading to significant effects on neurotransmitter systems, particularly those involving gamma-aminobutyric acid (GABA). This compound has been noted for its potential to induce sedation, muscle relaxation, and anxiolytic effects. However, due to its potency, it also carries a risk of dependence and adverse effects, including respiratory depression and overdose. Clonitazene is not widely used in clinical practice and is often associated with research contexts or illicit use. Its legal status varies by country, reflecting concerns over safety and potential for abuse. As with many substances in this category, careful handling and awareness of its effects are crucial for safety.
Formula:C20H23ClN4O2
InChI:InChI=1S/C20H23ClN4O2/c1-3-23(4-2)11-12-24-19-10-9-17(25(26)27)14-18(19)22-20(24)13-15-5-7-16(21)8-6-15/h5-10,14H,3-4,11-13H2,1-2H3
InChI key:InChIKey=GPZLDQAEBHTMPG-UHFFFAOYSA-N
SMILES:C(CN(CC)CC)N1C=2C(N=C1CC3=CC=C(Cl)C=C3)=CC(N(=O)=O)=CC2
Synonyms:
  • 1H-Benzimidazole-1-ethanamine, 2-[(4-chlorophenyl)methyl]-N,N-diethyl-5-nitro-
  • 2-(P-Chlorobenzyl-5-Nitrobenzimidazol-1-Yl)Ethyldiethylamine
  • 2-(p-Chlorobenzyl)-1-[2-(diethylamino)ethyl]-5-nitrobenzimidazole
  • 2-[(4-Chlorophenyl)methyl]-N,N-diethyl-5-nitro-1H-benzimidazole-1-ethanamine
  • 2-[2-(4-chlorobenzyl)-5-nitro-1H-benzimidazol-1-yl]-N,N-diethylethanamine
  • Benzimidazole, 2-(p-chlorobenzyl)-1-[2-(diethylamino)ethyl]-5-nitro-
  • C 193901
  • Clonitazene
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Found 2 products.
  • Clonitazene (1 mg/ml in Acetonitrile)
    TRC
    + Info

    Clonitazene (1 mg/ml in Acetonitrile)

    Controlled Product
    CAS:
    Formula:C20H23ClN4O2
    Color and Shape:Single Solution
    Molecular weight:386.88

    Ref: TR-KIT3755

    1x1ml
    127.00€
  • Clonitazene
    TRC
    + Info

    Clonitazene

    Controlled Product
    CAS:
    <p>Applications Clonitazene is an opioid analgesic of approximately three times the potency of morphine. It is used in opioid agonist/antagonist combinations for treatment of opioid receptor mediated diseases such as depression and pain.<br>References Deaver, D., et al.: U.S. Pat. Appl. Publ. US 20130281388 A1 20131024. Oct 24, 2013<br></p>
    Formula:C20H23ClN4O2
    Color and Shape:Neat
    Molecular weight:386.88

    Ref: TR-C587135

    10mg
    500.00€
    20mg
    939.00€
    2500µg
    125.00€