CAS 3862-25-7: 7α-Hydroxy-4-cholesten-3-one

Description: 7α-Hydroxy-4-cholesten-3-one, with the CAS number 3862-25-7, is a steroid compound that plays a significant role in cholesterol metabolism and is a key intermediate in the biosynthesis of bile acids. This compound features a hydroxyl group at the 7α position of the cholestene backbone, which contributes to its biological activity. It is typically found in various biological systems, including human tissues, where it is involved in the regulation of cholesterol levels and may influence lipid metabolism. The presence of the hydroxyl group enhances its solubility in biological fluids, facilitating its interaction with enzymes and receptors. Additionally, 7α-Hydroxy-4-cholesten-3-one is known to be a ligand for liver X receptors (LXRs), which are nuclear receptors that regulate genes involved in lipid homeostasis. Its structural characteristics, including the steroid framework and functional groups, are crucial for its biological functions and potential therapeutic applications in managing cholesterol-related disorders.

Formula: C₂₇H₄₄O₂

InChI: InChI=1S/C27H44O2/c1-17(2)7-6-8-18(3)21-9-10-22-25-23(12-14-27(21,22)5)26(4)13-11-20(28)15-19(26)16-24(25)29/h15,17-18,21-25,29H,6-14,16H2,1-5H3/t18-,21-,22+,23+,24-,25+,26+,27-/m1/s1

InChI key: InChIKey=IOIZWEJGGCZDOL-RQDYSCIWSA-N

SMILES: O=C1C=C2CC(O)C3C(CCC4(C)C(CCC34)C(C)CCCC(C)C)C2(C)CC1

Synonyms:

• (7Alpha,8Xi)-7-Hydroxycholest-4-En-3-One
• (7α)-7-Hydroxycholest-4-en-3-one
• 7α-Hydroxy-4-cholesten-3-one
• 7α-Hydroxycholest-4-en-3-one
• Cholest-4-En-3-One, 7-Hydroxy-, (7Alpha,8Xi)-
• Cholest-4-en-3-one, 7-hydroxy-, (7alpha)-
• Cholest-4-en-3-one, 7-hydroxy-, (7α)-
• Cholest-4-en-3-one, 7α-hydroxy-

(7R,8S,9S,10R,13R,14S,17R)-7-hydroxy-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one

CAS: 3862-25-7

• Formula: C₂₇H₄₄O₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 400.6371

Cholesterol Impurity 36

CAS: 3862-25-7

• Formula: C₂₇H₄₄O₂
• Molecular weight: 400.65

7α-Hydroxy-4-cholesten-3-one

CAS: 3862-25-7

• Purity: 99.13%
• Molecular weight: 400.64g/mol

Cholesterol Impurity 36-d7

CAS: 3862-25-7

• Formula: C₂₇H₃₇D₇O₂
• Molecular weight: 407.69

7α-Hydroxy-4-cholesten-3-one-d7 (contains 2% d0)

CAS: 3862-25-7

Applications Labelled 7α-Hydroxy-4-cholesten-3-one (H825130). 7α-Hydroxy-4-cholesten-3-one is a metabolite of Cholesterol (C432501). References Connor, W., et …

• Formula: C₂₇H₃₇D₇O₂
• Color and Shape: Neat
• Molecular weight: 407.68

7α-Hydroxy-4-cholesten-3-one

CAS: 3862-25-7

Applications 7α-Hydroxy-4-cholesten-3-one is a metabolite of Cholesterol (C432501). References Connor, W., et al.: J, Clin. …

• Formula: C₂₇H₄₄O₂
• Color and Shape: Neat
• Molecular weight: 400.64

7α-Hydroxy-4-cholesten-3-one-d7

CAS: 3862-25-7

Applications Labelled 7α-Hydroxy-4-cholesten-3-one (H825130). 7α-Hydroxy-4-cholesten-3-one is a metabolite of Cholesterol (C432501). References Connor, W., et …

• Formula: C₂₇H₃₇D₇O₂
• Color and Shape: White To Off-White
• Molecular weight: 407.68

7α-Hydroxy-4-cholesten-3-one

CAS: 3862-25-7

Intermediate in bile acids biosynthesis

• Formula: C₂₇H₄₄O₂
• Purity: Min. 98 Area-%
• Color and Shape: Powder
• Molecular weight: 400.64 g/mol

7-Hydroxy-4-cholesten-3-one-D7

CAS: 3862-25-7

Deuterated

• Formula: C₂₇H₄₄O₂
• Purity: Min. 95%
• Molecular weight: 400.64 g/mol

7α-Hydroxy-4-cholesten-3-one

CAS: 3862-25-7

7α-Hydroxy-4-cholesten-3-one is a PXR agonist that can be used to study diseases associated with defects …

• Formula: C₂₇H₄₄O₂
• Purity: 99.14%
• Color and Shape: White Solid
• Molecular weight: 400.64