CAS 38632-24-5
:Dopamine glucuronide
Description:
Dopamine glucuronide is a chemical compound formed through the conjugation of dopamine, a neurotransmitter, with glucuronic acid. This process, known as glucuronidation, typically occurs in the liver and serves to enhance the solubility of dopamine, facilitating its excretion from the body. The compound is characterized by its role in the metabolism of dopamine, which is crucial for various physiological functions, including mood regulation and motor control. Dopamine glucuronide is generally considered to be less active than its parent compound, dopamine, and is often used as a biomarker in pharmacokinetic studies to assess dopamine metabolism. Its structure includes a glucuronic acid moiety linked to the dopamine molecule, which alters its pharmacological properties. The compound is soluble in water due to the presence of the glucuronic acid, making it easier for the body to eliminate. Understanding dopamine glucuronide is important in the context of drug interactions and the metabolic pathways of neurotransmitters.
Formula:C14H19NO8
InChI:InChI=1S/C14H19NO8/c15-4-3-6-1-2-8(7(16)5-6)22-14-11(19)9(17)10(18)12(23-14)13(20)21/h1-2,5,9-12,14,16-19H,3-4,15H2,(H,20,21)/t9-,10-,11+,12-,14+/m0/s1
InChI key:InChIKey=CQASRCDNLNMIJY-BYNIDDHOSA-N
SMILES:O([C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O)C2=C(O)C=C(CCN)C=C2
Synonyms:- 4-(2-Aminoethyl)-2-hydroxyphenyl β-D-glucopyranosiduronic acid
- β-D-Glucopyranosiduronic acid, 4-(2-aminoethyl)-2-hydroxyphenyl
- Dopamine glucuronide
- Dopamine-4-O-glucuronide
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Found 3 products.
Dopamine 4-β-D-Glucuronide
CAS:Controlled Product<p>Applications A metabolite of Dopamine.<br>References Johnson, G., et al.: Life Sci., 26, 1591 (1980), Eisenhofer, G., et al.: J. Clin. Endocrinol. Metab., 82, 3864 (1997), Strassburg, C., et al.: Biochem. J., 338, 489 (1999), Alonen, A., et al.: Drug Metab. Dispos., 33, 657 (2005),<br></p>Formula:C14H19NO8Color and Shape:NeatMolecular weight:329.3Dopamine 4-β-D-Glucuronide-d4
CAS:Controlled ProductFormula:C14D4H15NO8Color and Shape:NeatMolecular weight:333.327

