CAS 38642-49-8

Benzoylpaeoniflorin

Description:

Benzoylpaeoniflorin is a chemical compound primarily derived from the roots of the peony plant, particularly Paeonia lactiflora. It is classified as a glycoside, which means it consists of a sugar moiety linked to a non-sugar component, in this case, benzoylpaeoniflorin. This compound is known for its potential pharmacological properties, including anti-inflammatory, analgesic, and neuroprotective effects. Its structure features a benzoyl group attached to paeoniflorin, which contributes to its biological activity. Benzoylpaeoniflorin has garnered interest in traditional medicine and modern pharmacology for its therapeutic potential, particularly in the treatment of various ailments. Additionally, it is often studied for its role in modulating biochemical pathways and its effects on cellular processes. As with many natural compounds, further research is necessary to fully elucidate its mechanisms of action and potential applications in medicine.

Formula: C₃₀H₃₂O₁₂

InChI: InChI=1/C30H32O12/c1-27-14-29(36)19-12-30(27,28(19,26(41-27)42-29)15-38-24(35)17-10-6-3-7-11-17)40-25-22(33)21(32)20(31)18(39-25)13-37-23(34)16-8-4-2-5-9-16/h2-11,18-22,25-26,31-33,36H,12-15H2,1H3/t18-,19-,20-,21+,22-,25+,26-,27+,28+,29-,30+/m1/s1

InChI key: InChIKey=LATYEZNGPQKAIK-HRCYFWENSA-N

SMILES: C(OC(=O)C1=CC=CC=C1)[C@@]23[C@@]4(O[C@@H]5O[C@H](COC(=O)C6=CC=CC=C6)[C@@H](O)[C@H](O)[C@H]5O)[C@@]7(C)O[C@@]2(O[C@@](O)([C@@]3(C4)[H])C7)[H]

Synonyms:

• 2,5-Methano-1H-3,4-dioxacyclobuta[cd]pentalene, β-<span class="text-smallcaps">D</span>-glucopyranoside deriv.
• [(1aR,2S,3aR,5R,5aR,5bS)-1a-[(6-O-benzoyl-beta-D-glucopyranosyl)oxy]-5-hydroxy-2-methyltetrahydro-1H-2,5-methano-3,4-dioxacyclobuta[cd]pentalen-5b(3aH)-yl]methyl benzoate
• beta-D-Glucopyranoside, 5b-((benzoyloxy)methyl)tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta(cd)pentalen-1a(2H)-yl, 6-benzoate, (1aR-(1aalpha,2beta,3aalpha,5alpha,5aalpha,5balpha))-
• {(3S,5R,6S)-1-({[(4,5-dihydroxycyclohex-2-en-1-yl)carbonyl]oxy}methyl)-3-[(1aR)-1H-3,4-dioxacyclobuta[cd]pentalen-1a(2H)-yloxy]-5,6-dihydroxy-4-methyl-2-oxabicyclo[2.2.1]hept-3-yl}methyl benzoate
• β-<span class="text-smallcaps">D</span>-Glucopyranoside, (1aR,2S,3aR,5R,5aR,5bS)-5b-[(benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1a(2H)-yl, 6-benzoate
• β-<span class="text-smallcaps">D</span>-Glucopyranoside, 5b-[(benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1a(2H)-yl, 6-benzoate, [1aR-(1aα,2β,3aα,5α,5aα,5bα)]-
• β-D-Glucopyranoside, (1aR,2S,3aR,5R,5aR,5bS)-5b-[(benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1a(2H)-yl, 6-benzoate
• β-D-Glucopyranoside, 5b-[(benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1a(2H)-yl, 6-benzoate, [1aR-(1aα,2β,3aα,5α,5aα,5bα)]-
• 2,5-Methano-1H-3,4-dioxacyclobuta[cd]pentalene, β-D-glucopyranoside deriv.
• Benzoylpaeoniflorin
• ((2S,2aR,2a1S,3aR,4R,5aR)-2a-(((2S,3R,4S,5S,6R)-6-((benzoyloxy)methyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)-4-hydroxy-2-methylhexahydro-2H-1,5-dioxa-2,4-methanocyclobuta[cd]pentalen-2a1-yl)methyl benzoate
• Paeoniflorin Benzoyl Impurity
• Benzoylpaeoniflorin, >99%

Benzoylpaeoniflorin

CAS: 38642-49-8

Formula: C₃₀H₃₂O₁₂

Purity: 99%

Color and Shape: Solid

Molecular weight: 584.5679

Ref: IN-DA00BXVY

Benzoylpaeoniflorin

CAS: 38642-49-8

Formula: C₃₀H₃₂O₁₂

Molecular weight: 584.57

Ref: 7W-GY1203

Benzoylpaeoniflorin

CAS: 38642-49-8

Benzoylpaeoniflorin

Purity: ≥95%

Molecular weight: 584.57g/mol

Ref: 54-BUP00106

Benzoylpaeoniflorin

CAS: 38642-49-8

Benzoylpaeoniflorin

Purity: 98%

Molecular weight: 584.57g/mol

Ref: 54-OR1022934

Benzoylpaeoniflorin

CAS: 38642-49-8

Benzoylpaeoniflorin can restrain apoptosis of rats with coronary heart diseases by increasing the levels of Bc1-2 and decreasing the levels of Bax, suggesting that it may treat coronary heart disease by decreasing apoptosis.

Formula: C₃₀H₃₂O₁₂

Purity: 95%~99%

Color and Shape: White cryst.

Molecular weight: 584.574

Ref: BP-BP0248

Benzoylpaeoniflorin

CAS: 38642-49-8

1. Benzoylpaeoniflorin is active against cyclooxygenase-1 and cyclooxygenase-2 enzymes.

Formula: C₃₀H₃₂O₁₂

Purity: 95.86% - 97.28%

Color and Shape: Solid

Molecular weight: 584.57

Ref: TM-T6S1652

Benzoylpaeoniflorin

CAS: 38642-49-8

Benzoylpaeoniflorin is a glycoside, which is a naturally occurring compound found in certain plants. It is primarily sourced from the roots of *Paeonia lactiflora*, a herbaceous plant commonly used in traditional medicine. The compound exerts its effects through several mechanisms, including the inhibition of inflammatory mediators and modulation of oxidative stress pathways. Benzoylpaeoniflorin acts by targeting specific signaling pathways that regulate inflammation and cellular stress responses, contributing to its therapeutic potential.

Formula: C₃₀H₃₂O₁₂

Purity: Min. 95%

Color and Shape: White Off-White Powder

Molecular weight: 584.57 g/mol

Ref: 3D-MB31310

Benzoylpaeoniflorin

Controlled Product

CAS: 38642-49-8

Applications Benzoylpaeoniflorin is a derivative of Paeoniflorin (P133830), a monoterpene glycoside with potential anti-inflammatory activity. Paeoniflorin inhibits monocyte phagocytosis, or the TNF-α and PGE-2 production of monocytes.
References Zhu, X. et al.: Nat. Prod. Res., 28, 301(2014); Di, W. et al.: Int. Immunopharmacol.,, 14, 172 (2012);

Formula: C₃₀H₃₂O₁₂

Color and Shape: Off-White

Molecular weight: 584.57

Ref: TR-B208325