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CAS 38677-81-5

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(±)-Pirbuterol

Description:
(±)-Pirbuterol is a synthetic compound classified as a selective β2-adrenergic agonist, primarily used in the management of asthma and chronic obstructive pulmonary disease (COPD). It acts by stimulating β2-adrenergic receptors in the bronchial smooth muscle, leading to bronchodilation and improved airflow. The substance is characterized by its chiral nature, existing as a racemic mixture of two enantiomers, which can influence its pharmacological activity and side effects. (±)-Pirbuterol is typically administered via inhalation, allowing for targeted delivery to the lungs, and is known for its rapid onset of action. Its chemical structure includes a phenolic group and a secondary amine, contributing to its activity and solubility properties. The compound is generally well-tolerated, though potential side effects may include tremors, tachycardia, and nervousness, which are common to β2-agonists. As with any medication, it is essential to use (±)-Pirbuterol under medical supervision to ensure safety and efficacy in treating respiratory conditions.
Formula:C12H20N2O3
InChI:InChI=1S/C12H20N2O3/c1-12(2,3)13-6-11(17)8-4-5-10(16)9(7-15)14-8/h4-5,11,13,15-17H,6-7H2,1-3H3
InChI key:InChIKey=VQDBNKDJNJQRDG-UHFFFAOYSA-N
SMILES:C(CNC(C)(C)C)(O)C=1N=C(CO)C(O)=CC1
Synonyms:
  • (±)-Pirbuterol
  • α6-[[(1,1-Dimethylethyl)amino]methyl]-3-hydroxy-2,6-pyridinedimethanol
  • ARA 211
  • Pirbuterol
  • 2,6-Pyridinedimethanol, α6-[[(1,1-dimethylethyl)amino]methyl]-3-hydroxy-
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