DMT-thymidine H-phosphonate triethylammonium, with the CAS number 3868-27-7, is a chemical compound that serves as a phosphonate derivative of thymidine, a nucleoside component of DNA. This compound is characterized by the presence of a dimethoxytrityl (DMT) protecting group, which is commonly used in the synthesis of oligonucleotides to protect the hydroxyl group of the nucleoside. The H-phosphonate moiety indicates that it contains a phosphonate group, which is a key feature in the formation of phosphodiester bonds during nucleic acid synthesis. The triethylammonium component suggests that the compound is in a salt form, enhancing its solubility in polar solvents. DMT-thymidine H-phosphonate triethylammonium is utilized in various biochemical applications, particularly in the field of molecular biology for the synthesis of DNA and RNA sequences. Its stability and reactivity make it a valuable intermediate in the production of oligonucleotides, facilitating the study of genetic material and the development of therapeutic agents.

dmt-thymidine H-phosphonate*triethylammonium

3868-27-7: DMT-thymidine H-phosphonate triethylammonium, with the CAS number 3868-27-7, is a chemical compound that serves as a phosphonate derivative of thymidine, a nucleoside component of DNA. This compound is characterized by the presence of a dimethoxytrityl (DMT) protecting group, which is commonly used in the synthesis of oligonucleotides to protect the hydroxyl group of the nucleoside. The H-phosphonate moiety indicates that it contains a phosphonate group, which is a key feature in the formation of phosphodiester bonds during nucleic acid synthesis. The triethylammonium component suggests that the compound is in a salt form, enhancing its solubility in polar solvents. DMT-thymidine H-phosphonate triethylammonium is utilized in various biochemical applications, particularly in the field of molecular biology for the synthesis of DNA and RNA sequences. Its stability and reactivity make it a valuable intermediate in the production of oligonucleotides, facilitating the study of genetic material and the development of therapeutic agents.

<p>5'- O- [Bis(4- methoxyphenyl) phenylmethyl] - thymidine 3'- (hydrogen phosphonate) ,compd. with N, N- diethylethanamine (1:1) is a novel monophosphate nucleoside that has been synthesized and evaluated in vitro as an anticancer agent. It inhibits the proliferation of various human tumor cell lines, including breast cancer cells. This compound is also active against HIV-1 virus but not against other viruses tested. 5'- O- [Bis(4- methoxyphenyl) phenylmethyl] - thymidine 3'- (hydrogen phosphonate) ,compd. with N, N- diethylethanamine (1:1), like other nucleosides, can be modified to suit particular needs and then used for therapeutic purposes.</p>

CAS 3868-27-7

dmt-thymidine H-phosphonate*triethylammonium

5'- O- [Bis(4- methoxyphenyl) phenylmethyl] - thymidine 3'- (hydrogen phosphonate) ,compd. with N, N- diethylethanamine (1:1)

Ref: 3D-NT158343